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AB120802

SC-66, Allosteric Akt inhibitor

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MW 276.34 g/mol, Purity >99%. Allosteric Akt inhibitor. Interferes with PIP3 binding to Akt's PH domain. Additionally facilitates Akt ubiquitination. Displays anticancer activity in vitro and in vivo.
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Chemical Structure - SC-66, Allosteric Akt inhibitor (AB120802)
  • Chemical Structure

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Chemical Structure - SC-66, Allosteric Akt inhibitor (AB120802)

2D chemical structure image of ab120802, SC-66, Allosteric Akt inhibitor

Key facts

CAS number

871361-88-5

Purity

>99%

Form

Solid

form

Molecular weight

276.34 g/mol

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>1</sub><sub>6</sub>N<sub>2</sub>O

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Soluble in ethanol to 50 mM

Biological description

Allosteric Akt inhibitor. Interferes with PIP3 binding to Akt's PH domain. Additionally facilitates Akt ubiquitination. Displays anticancer activity in vitro and in vivo.

IUPAC Name

(2E,6E)-2,6-Bis(4-pyridinylmethylene)cyclohexanone

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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