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AB222375

SCR7 pyrazine, NHEJ inhibitor

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MW 332.4 Da, Purity >98%. Small molecule nonhomologous end-joining (NHEJ) inhibitor. SCR7 analog. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.

Key facts

CAS number

14892-97-8

Purity

>98%

Form

Solid

form

Molecular weight

332.4 Da

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>1</sub><sub>2</sub>N<sub>4</sub>OS

PubChem

10688007

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 20 mM

Biochemical name

SCR7 pyrazine

Biological description

Small molecule nonhomologous end-joining (NHEJ) inhibitor. SCR7 analog. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.

Canonical smiles

C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4

InChi

InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)

InChiKey

GSRTWXVBHGOUBU-UHFFFAOYSA-N

IUPAC Name

6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called B1119 SCR7 pyrazine. B1119-25 is the same size as the 25 mg size of ab222375.
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark|Store under desiccating conditions
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Product protocols

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