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AB120836

SD 169, ATP-competitive p38alpha MAPK inhibitor

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MW 160.17 Da, Purity >99%. Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.
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Chemical Structure - SD 169, ATP-competitive p38alpha MAPK inhibitor (AB120836)
  • Chemical Structure

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Chemical Structure - SD 169, ATP-competitive p38alpha MAPK inhibitor (AB120836)

2D chemical structure image of ab120836, SD 169, ATP-competitive p38alpha MAPK inhibitor

Key facts

CAS number

1670-87-7

Purity

>99%

Form

Solid

form

Molecular weight

160.17 Da

Molecular formula

C<sub>9</sub>H<sub>8</sub>N<sub>2</sub>O

PubChem

14973220

Nature

Synthetic

Solubility

Soluble in water to 5 mM

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

1H-Indole-5-carboxamide

Biological description

Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.

Canonical smiles

C1=CC2=C(C=CN2)C=C1C(=O)N

InChi

InChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)

InChiKey

GQMYQEAXTITUAE-UHFFFAOYSA-N

IUPAC Name

1H-indole-5-carboxamide

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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