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MW 160.17 Da, Purity >99%. Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.

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Images

Chemical Structure - SD 169, ATP-competitive p38alpha MAPK inhibitor (AB120836), expandable thumbnail

Key facts

CAS number
1670-87-7
Purity
> 99%
Form
Solid
Molecular weight
160.17 Da
Molecular formula
C9H8N2O
PubChem identifier
14973220
Nature
Synthetic

Target data

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MW 160.17 Da, Purity >99%. Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.

Key facts

Purity
> 99%
PubChem identifier
14973220
Solubility

Soluble in water to 5 mM.

Soluble in ethanol to 100 mM.

Soluble in DMSO to 100 mM.

Biochemical name
1H-Indole-5-carboxamide
Biological description

Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.

Canonical SMILES
C1=CC2=C(C=CN2)C=C1C(=O)N
InChI
InChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChIKey
GQMYQEAXTITUAE-UHFFFAOYSA-N
IUPAC name
1H-indole-5-carboxamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - SD 169, ATP-competitive p38alpha MAPK inhibitor (ab120836), expandable thumbnail

    Chemical Structure - SD 169, ATP-competitive p38alpha MAPK inhibitor (ab120836)

    2D chemical structure image of ab120836, SD 169, ATP-competitive p38alpha MAPK inhibitor

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Product protocols

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