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AB147472

SKF 83566 hydrobromide, D1 receptor antagonist (DMSO solution)

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MW 413.1 Da, Purity >99%. Potent, selective D1 receptor antagonist (Ki = 0.4 nM). Centrally active following systemic administration. Various neurological effects in vitro and in vivo.

View Alternative Names

ERK-2, ERT1, Extracellular signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MK01_HUMAN, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, P38, P41, PRKM 2, PRKM1, p42-MAPK, protein kinase, mitogen-activated, 1, protein kinase, mitogen-activated, 2, protein tyrosine kinase ERK2

Key facts

CAS number

108179-91-5

Purity

>99%

Form

Liquid

form

Molecular weight

413.1 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>1</sub><sub>9</sub>Br<sub>2</sub>NO

PubChem

23581817

Nature

Synthetic

Biochemical name

SKF 83566 hydrobromide

Biological description

Potent, selective D1 receptor antagonist (Ki = 0.4 nM). Centrally active following systemic administration. Various neurological effects in vitro and in vivo.

Canonical smiles

CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br.Br

InChi

InChI=1S/C17H18BrNO.BrH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H

InChiKey

SDQJYYGODYRPBR-UHFFFAOYSA-N

IUPAC Name

8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrobromide

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

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Complementary Products

Biochemicals

AB147476

Medetomidine hydrochloride, alpha2 adrenoceptor agonist (aqueous solution)

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Primary Antibodies

AB106649

Anti-N4BP1 antibody

Western blot - Anti-N4BP1 antibody (AB106649)

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Biochemicals

AB141146

SKF 83566 hydrobromide, D1 receptor antagonist

Chemical Structure - SKF 83566 hydrobromide, D1 receptor antagonist (AB141146)

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Primary Antibodies

AB71916

Anti-EpCAM antibody

BOND RX™ Validated

Immunocytochemistry/ Immunofluorescence - Anti-EpCAM antibody (AB71916)

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