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MW 291.77 Da, Purity >98%. D1-like dopamine receptor agonist. pKi values are 9 (D1), 6.8 (D2), 5.3 (D3), 6.0 (D4) and 9.3 (D5). Ki values are 151 and 2364 nM for D1-like and D2-like dopamine receptors, respectively. Centrally active upon systemic administration.
Alternative names=3',5'-cyclic AMP synthetase, AC-III, AC2, AC6, ACVI, ADCY3_HUMAN, ADCY6_HUMAN, ADCYB, ALR_HUMAN, ATP pyrophosphate lyase 2, ATP pyrophosphate-lyase, ATP pyrophosphate-lyase 3, ATP pyrophosphate-lyase 6, ATP pyrophosphate-lyase 8, Adenylate cyclase, Adenylate cyclase 2, Adenylate cyclase 2 (brain), Adenylate cyclase 6, Adenylate cyclase 8, Adenylate cyclase II, Adenylate cyclase type 2, Adenylate cyclase type 3, Adenylate cyclase type 6, Adenylate cyclase type II, Adenylate cyclase type III, Adenylate cyclase type VI, Adenylate cyclase type VIII, Adenylyl cyclase 3, Adenylyl cyclase 6, Adenylyl cyclase 8 brain, Augmenter of liver regeneration, Brain adenylate cyclase 8, Ca(2+)-inhibitable adenylyl cyclase, Ca(2+)/calmodulin-activated adenylyl cyclase, D(1A) dopamine receptor, D(1B) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, D(5) dopamine receptor, D1 beta dopamine receptor, D1A dopamine receptor, D1B dopamine receptor, D2 dopamine receptor, D2DR, D2R, D5 dopamine receptor, DADR, DBDR, DKFZp779F075, DRD 1A, DRD 1B, DRD1L2, DRD1_HUMAN, DRD2_HUMAN, DRD5_HUMAN, Dopamine D1 receptor, Dopamine D2 receptor, Dopamine D3 receptor, Dopamine D5 receptor, Dopamine receptor D1B, Dopamine receptor D2, EC 4.6.1.1, ERV1, ERV1 homolog, Eag-related protein 1, Erv1 like growth factor, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, FAD-linked sulfhydryl oxidase ALR, FLJ16822, FLJ45092, GFER, Growth factor augmenter of liver regeneration, Growth factor erv1 like, H-ERG, HBAC1, HBAC2, HPO, HPO1, HPO2, HSS, Hepatic regenerative stimulation substance, Hepatopoietin, Hepatopoietin protein, KCNH2_HUMAN, KIAA0422, KIAA1060, Kv11.1, LQT 2, MGC10601, MGC133314, Particulate Guanylate Cyclase E, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, SQT1, Type II adenylate cyclase, Voltage gated potassium channel, subfamily H, member 2, Voltage-gated potassium channel subunit Kv11.1, adenylate cyclase 3, dopamine receptor D1, dopamine receptor D5, eag homolog, hERG-1, hERV1, olfactive type
- CAS number
62717-42-4
- Purity
> 98%
- Form
Solid
- Molecular weight
291.77 Da
- Molecular formula
C16H18ClNO2
- PubChem identifier
147514
- Nature
Synthetic
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MW 291.77 Da, Purity >98%. D1-like dopamine receptor agonist. pKi values are 9 (D1), 6.8 (D2), 5.3 (D3), 6.0 (D4) and 9.3 (D5). Ki values are 151 and 2364 nM for D1-like and D2-like dopamine receptors, respectively. Centrally active upon systemic administration.
Alternative names=3',5'-cyclic AMP synthetase, AC-III, AC2, AC6, ACVI, ADCY3_HUMAN, ADCY6_HUMAN, ADCYB, ALR_HUMAN, ATP pyrophosphate lyase 2, ATP pyrophosphate-lyase, ATP pyrophosphate-lyase 3, ATP pyrophosphate-lyase 6, ATP pyrophosphate-lyase 8, Adenylate cyclase, Adenylate cyclase 2, Adenylate cyclase 2 (brain), Adenylate cyclase 6, Adenylate cyclase 8, Adenylate cyclase II, Adenylate cyclase type 2, Adenylate cyclase type 3, Adenylate cyclase type 6, Adenylate cyclase type II, Adenylate cyclase type III, Adenylate cyclase type VI, Adenylate cyclase type VIII, Adenylyl cyclase 3, Adenylyl cyclase 6, Adenylyl cyclase 8 brain, Augmenter of liver regeneration, Brain adenylate cyclase 8, Ca(2+)-inhibitable adenylyl cyclase, Ca(2+)/calmodulin-activated adenylyl cyclase, D(1A) dopamine receptor, D(1B) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, D(5) dopamine receptor, D1 beta dopamine receptor, D1A dopamine receptor, D1B dopamine receptor, D2 dopamine receptor, D2DR, D2R, D5 dopamine receptor, DADR, DBDR, DKFZp779F075, DRD 1A, DRD 1B, DRD1L2, DRD1_HUMAN, DRD2_HUMAN, DRD5_HUMAN, Dopamine D1 receptor, Dopamine D2 receptor, Dopamine D3 receptor, Dopamine D5 receptor, Dopamine receptor D1B, Dopamine receptor D2, EC 4.6.1.1, ERV1, ERV1 homolog, Eag-related protein 1, Erv1 like growth factor, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, FAD-linked sulfhydryl oxidase ALR, FLJ16822, FLJ45092, GFER, Growth factor augmenter of liver regeneration, Growth factor erv1 like, H-ERG, HBAC1, HBAC2, HPO, HPO1, HPO2, HSS, Hepatic regenerative stimulation substance, Hepatopoietin, Hepatopoietin protein, KCNH2_HUMAN, KIAA0422, KIAA1060, Kv11.1, LQT 2, MGC10601, MGC133314, Particulate Guanylate Cyclase E, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, SQT1, Type II adenylate cyclase, Voltage gated potassium channel, subfamily H, member 2, Voltage-gated potassium channel subunit Kv11.1, adenylate cyclase 3, dopamine receptor D1, dopamine receptor D5, eag homolog, hERG-1, hERV1, olfactive type
Key facts
- CAS number
62717-42-4
- Purity
> 98%
- Form
Solid
- Molecular weight
291.77 Da
- Molecular formula
C16H18ClNO2
- PubChem identifier
147514
- Nature
Synthetic
- Biochemical name
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, hydrochloride
- Biological description
D1-like dopamine receptor agonist. pKi values are 9 (D1), 6.8 (D2), 5.3 (D3), 6.0 (D4) and 9.3 (D5). Ki values are 151 and 2364 nM for D1-like and D2-like dopamine receptors, respectively. Centrally active upon systemic administration.
- Canonical SMILES
C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3.Cl
- InChI
InChI=1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H
- InChIKey
YEWHJCLOUYPAOH-UHFFFAOYSA-N
- IUPAC name
5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;hydrochloride
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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