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AB120386

Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor

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(2 Publications)

MW 183.91 g/mol. Broad spectrum inhibitor of protein tyrosine phosphatases. Also inhibits ATPases. Inhibits apoptosis. Chemical precursor to decavanadate, which is formed at acidic pH; inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding.
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Chemical Structure - Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor (AB120386)
  • Chemical Structure

Lab

Chemical Structure - Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor (AB120386)

2D chemical structure image of ab120386, Sodium orthovanadate (for Decavanadate solution), tyrosine phosphatase inhibitor

Key facts

CAS number

13721-39-6

Form

Solid

form

Molecular weight

183.91 g/mol

Molecular formula

Na<sub>3</sub>VO<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Broad spectrum inhibitor of protein tyrosine phosphatases. Also inhibits ATPases. Inhibits apoptosis. Chemical precursor to decavanadate, which is formed at acidic pH; inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding.

InChiKey

HQHUIUQMQXUPHI-UHFFFAOYSA-N

IUPAC Name

Sodium orthovanadate

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Complementary Products

Biochemicals

AB141032

PMSF, protease inhibitor

Cellular Activation - PMSF, protease inhibitor (AB141032)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
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Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

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Assay Kits

AB238544

Comet Assay Kit (3-well slides)

Fluorescence Microscopy - Comet Assay Kit (3-well slides) (AB238544)

  • 4
  • 2
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cellular and infection microbiology 14:1374659 PubMed38524184

2024

infection-induced host cellular DNA damage is strain-dependent and leads to the activation of the ATM-dependent homologous recombination pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lisbeth Rojas-Barón,Carlos Hermosilla,Anja Taubert,Zahady D Velásquez

Frontiers in microbiology 15:1336267 PubMed38450167

2024

Me49 and NED strains arrest host cell cycle progression and alter chromosome segregation in a strain-independent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Lisbeth Rojas-Barón,Carlos Hermosilla,Anja Taubert,Zahady D Velásquez
View all publications
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