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AB145202

Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator

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MW 419.2 g/mol, Purity >98%. cAMP analog. Cell-permeable, potent activator of cAMP-dependent protein kinase (PKA; Ka = 30 nM); Selective for PKA over cGMP-dependent protein kinase (PKG; Ka = 10 μM). Not significantly hydrolyzed by type I, II or III phosphodiesterases.
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Chemical Structure - Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator (AB145202)
  • Chemical Structure

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Chemical Structure - Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator (AB145202)

2D chemical structure image of ab145202, Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator

Key facts

CAS number

120912-54-1

Purity

>98%

Molecular weight

419.2 g/mol

Molecular formula

C<sub>1</sub><sub>2</sub>H<sub>1</sub><sub>0</sub>NaN<sub>2</sub>O<sub>5</sub>PSCl<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in water to 25 mM

Biological description

cAMP analog. Cell-permeable, potent activator of cAMP-dependent protein kinase (PKA; Ka = 30 nM); Selective for PKA over cGMP-dependent protein kinase (PKG; Ka = 10 μM). Not significantly hydrolyzed by type I, II or III phosphodiesterases.

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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