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AB145613

SPDP crosslinker, Cysteine and primary amine reactive short chain crosslinker

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MW 312.4 Da, Purity >90%. Cysteine and primary amine reactive short chain crosslinker. Induces amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
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Chemical Structure - SPDP crosslinker, Cysteine and primary amine reactive short chain crosslinker (AB145613)
  • Chemical Structure

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Chemical Structure - SPDP crosslinker, Cysteine and primary amine reactive short chain crosslinker (AB145613)

2D chemical structure image of ab145613, SPDP crosslinker, Cysteine and primary amine reactive short chain crosslinker

Key facts

CAS number

68181-17-9

Purity

>90%

Form

Solid

form

Molecular weight

312.4 Da

Molecular formula

C<sub>1</sub><sub>2</sub>H<sub>1</sub><sub>2</sub>N<sub>2</sub>O<sub>4</sub>S<sub>2</sub>

PubChem

100682

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

N-Succinimidyl 3-(2-pyridyldithio)propionate

Biological description

Cysteine and primary amine reactive short chain crosslinker. Induces amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Canonical smiles

C1CC(=O)N(C1=O)OC(=O)CCSSC2=CC=CC=N2

InChi

InChI=1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2

InChiKey

JWDFQMWEFLOOED-UHFFFAOYSA-N

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3-(pyridin-2-yldisulfanyl)propanoate

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2328 SPDP Crosslinker. 2328-250 is the same size as the 250 mg size of ab145613.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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