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AB146523

Spermine tetrahydrochloride, polyamine used for precipitation of DNA

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MW 348.19 g/mol. Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure. Spermine tetrahydrochloride is used for precipitation of DNA from low salt aqueous buffers.
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Chemical Structure - Spermine tetrahydrochloride, polyamine used for precipitation of DNA (AB146523)
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Chemical Structure - Spermine tetrahydrochloride, polyamine used for precipitation of DNA (AB146523)

2D chemical structure image of ab146523, Spermine tetrahydrochloride, polyamine used for precipitation of DNA

Key facts

CAS number

306-67-2

Form

Powder

form

Molecular weight

348.19 g/mol

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>2</sub><sub>6</sub>N<sub>4</sub>.<sub>4</sub>HCl

Nature

Synthetic

Solubility

Soluble in water to 1 M

Biological description

Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure. Spermine tetrahydrochloride is used for precipitation of DNA from low salt aqueous buffers.

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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