JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB146174

SR-9009, REV-ERBalpha/beta agonist

Be the first to review this product! Submit a review

|

(0 Publication)

MW 437.94 g/mol. Potent REV-ERBα/β agonist (IC50 values are 670 and 800 nM for Rev-ErbAα and Rev-ErbAβ-dependent repressor activity respectively). Modulates circadian behavior, shows antiobesogenic and anti-inflammatory effects in vivo. .
1 Images
Chemical Structure - SR-9009, REV-ERBalpha/beta agonist (AB146174)
  • Chemical Structure

Lab

Chemical Structure - SR-9009, REV-ERBalpha/beta agonist (AB146174)

2D chemical structure image of ab146174, SR-9009, REV-ERBalpha/beta agonist

Key facts

CAS number

1379686-30-2

Molecular weight

437.94 g/mol

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>2</sub><sub>4</sub>ClN<sub>3</sub>O<sub>4</sub>S

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Potent REV-ERBα/β agonist (IC50 values are 670 and 800 nM for Rev-ErbAα and Rev-ErbAβ-dependent repressor activity respectively). Modulates circadian behavior, shows antiobesogenic and anti-inflammatory effects in vivo.

Canonical smiles

CCOC(=O)N1CCC(C1)CN(CC2=CC=C(C=C2)CL)CC3=CC=C(S3)[N+](=O)[O-]

InChi

InChI=1S/C20H24ClN3O4S/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27/h3-8,16H,2,9-14H2,1H3

InChiKey

MMJJNHOIVCGAAP-UHFFFAOYSA-N

IUPAC Name

Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate

style
left-column

Complementary Products

Biochemicals

AB146173

SR-8278, REV-ERBalpha antagonist

Chemical Structure - SR-8278, REV-ERBalpha antagonist (AB146173)

  • 0
  • 0
Biochemicals

AB120121

D-Cycloserine, NMDA glycine site agonist

Chemical Structure - D-Cycloserine, NMDA glycine site agonist (AB120121)

  • 0
  • 0
Assay Kits

AB139483

Golgi Staining Kit - Green Fluorescence - Cytopainter

Fluorescence Microscopy - Golgi Staining Kit - Green Fluorescence - Cytopainter (AB139483)

  • 0
  • 0
Biochemicals

AB144576

ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor

Chemical Structure - ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor (AB144576)

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com