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AB145648

STA-21 (Ochromycinone), STAT3 inhibitor

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MW 306.3 Da, Purity >98%. Selective STAT3 inhibitor. Shows antiproliferative effects (IC50 values are 12.2 and 18.7 μM for DU145 and PC3 cell lines respectively). Shows anti-inflammatory effects in vivo. .
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Chemical Structure - STA-21 (Ochromycinone), STAT3 inhibitor (AB145648)
  • Chemical Structure

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Chemical Structure - STA-21 (Ochromycinone), STAT3 inhibitor (AB145648)

2D chemical structure image of ab145648, STA-21 (Ochromycinone), STAT3 inhibitor

Key facts

CAS number

28882-53-3

Purity

>98%

Form

Solid

form

Molecular weight

306.3 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>1</sub><sub>4</sub>O<sub>4</sub>

PubChem

11808929

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Biochemical name

Ochromycinone

Biological description

Selective STAT3 inhibitor. Shows antiproliferative effects (IC50 values are 12.2 and 18.7 μM for DU145 and PC3 cell lines respectively). Shows anti-inflammatory effects in vivo.

Canonical smiles

CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O

Isomeric smiles

C[C@H]1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O

InChi

InChI=1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3/t9-/m0/s1

InChiKey

ZAWXOCUFQSQDJS-VIFPVBQESA-N

IUPAC Name

(3S)-8-hydroxy-3-methyl-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione

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Complementary Products

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Primary Antibodies

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Anti-SIRP alpha antibody [EPR16264]

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Biochemicals

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CCT-251921

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Biochemicals

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Fumagillin, methionine aminopeptidase-2 (MetAP2) inhibitor

Chemical Structure - Fumagillin, methionine aminopeptidase-2 (MetAP2) inhibitor (AB141527)

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2626 STA-21. 2626-250 is the same size as the 250 µg size of ab145648.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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