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MW 429.5 Da, Purity >98%. Cell-permeable, potent aryl hydrocarbon receptor antagonist (IC50 = 127 nM). Used for hematopoietic differentiation of iPSCs. Active in vitro and in vivo.

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Images

Chemical Structure - StemRegenin 1 hydrochloride, AhR antagonist (AB142174), expandable thumbnail

Key facts

CAS number
1227633-49-9
Purity
> 98%
Form
Solid
Molecular weight
429.5 Da
Molecular formula
C24H23N5OS
PubChem identifier
46199207
Nature
Synthetic

Target data

Recommended products

MW 429.5 Da, Purity >98%. Cell-permeable, potent aryl hydrocarbon receptor antagonist (IC50 = 127 nM). Used for hematopoietic differentiation of iPSCs. Active in vitro and in vivo.

Key facts

Purity
> 98%
PubChem identifier
46199207
Solubility

Soluble in DMSO to 100 mM (with warming).

Biochemical name
StemRegenin 1
Biological description

Cell-permeable, potent aryl hydrocarbon receptor antagonist (IC50 = 127 nM). Used for hematopoietic differentiation of iPSCs. Active in vitro and in vivo.

Canonical SMILES
CC(C)N1C=NC2=C(N=C(N=C21)C3=CSC4=CC=CC=C43)NCCC5=CC=C(C=C5)O
InChI
InChI=1S/C24H23N5OS/c1-15(2)29-14-26-21-23(25-12-11-16-7-9-17(30)10-8-16)27-22(28-24(21)29)19-13-31-20-6-4-3-5-18(19)20/h3-10,13-15,30H,11-12H2,1-2H3,(H,25,27,28)
InChIKey
BGFHMYJZJZLMHW-UHFFFAOYSA-N
IUPAC name
4-[2-[[2-(1-benzothiophen-3-yl)-9-propan-2-ylpurin-6-yl]amino]ethyl]phenol

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Notes

This product is manufactured by BioVision, an Abcam company and was previously called 1967 StemRegenin 1. 1967-5 is the same size as the 5 mg size of ab142174.

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1 product image

  • Chemical Structure - StemRegenin 1 hydrochloride, AhR antagonist (ab142174), expandable thumbnail

    Chemical Structure - StemRegenin 1 hydrochloride, AhR antagonist (ab142174)

    2D chemical structure image of ab142174, StemRegenin 1 hydrochloride, AhR antagonist

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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