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MW 322.27 Da, Purity >=98%. STING Antagonist (C-178) is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

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Key facts

CAS number
329198-87-0
Purity
>= 98%
Form
Solid
Molecular weight
322.27 Da
Molecular formula
C17H10N2O5
PubChem identifier
2866412
Nature
Synthetic

Target data

Recommended products

MW 322.27 Da, Purity >=98%. STING Antagonist (C-178) is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

Key facts

Purity
>= 98%
PubChem identifier
2866412
Solubility

Soluble in DMSO to >75 mM.

Biochemical name
N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide
Biological description

STING Antagonist (C-178) is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

Canonical SMILES
C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]
InChI
InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)
InChIKey
URUVDCCYSJEGQQ-UHFFFAOYSA-N
IUPAC name
N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C

Notes

This product is manufactured by BioVision, an Abcam company and was previously called B2396 STING Antagonist, C-178. B2396-5 is the same size as the 5 mg size of ab287033.

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