JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB287033

STING Antagonist (C-178)

Be the first to review this product! Submit a review

|

(0 Publication)

MW 322.27 Da, Purity >98%. STING Antagonist (C-178) is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

Key facts

CAS number

329198-87-0

Purity

>98%

Form

Solid

form

Molecular weight

322.27 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>1</sub><sub>0</sub>N<sub>2</sub>O<sub>5</sub>

PubChem

2866412

Nature

Synthetic

Solubility

Soluble in DMSO to >75 mM

Biochemical name

N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide

Biological description

STING Antagonist (C-178) is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.

Canonical smiles

C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]

InChi

InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)

InChiKey

URUVDCCYSJEGQQ-UHFFFAOYSA-N

IUPAC Name

N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide

style
left-column

Product details

This product is manufactured by BioVision, an Abcam company and was previously called B2396 STING Antagonist, C-178. B2396-5 is the same size as the 5 mg size of ab287033.
style
left-column

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Complementary Products

Biochemicals

AB230375

G10, STING signaling activator

Chemical Structure - G10, STING signaling activator (AB230375)

  • 0
  • 0
Biochemicals

AB287088

RU-521

  • 0
  • 0
Primary Antibodies

AB198952

Alexa Fluor® 647 Anti-STING antibody [EPR13130]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-STING antibody [EPR13130] (AB198952)

  • 4
  • 1
Biochemicals

AB120067

LY 367385, mGlu1a antagonist

Chemical Structure - LY 367385, mGlu1a antagonist (AB120067)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com