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AB285438

STING Inhibitor, C-176

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MW 358.09 Da, Purity >98%. STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.

Key facts

CAS number

314054-00-7

Purity

>98%

Form

Solid

form

Molecular weight

358.09 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>7</sub>IN<sub>2</sub>O<sub>4</sub>

PubChem

1103958

Nature

Synthetic

Solubility

Soluble in DMSO to >10mM

Biochemical name

N-(4-iodophenyl)-5-nitrofuran-2-carboxamide

Biological description

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.

Canonical smiles

C1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])I

InChi

InChI=1S/C11H7IN2O4/c12-7-1-3-8(4-2-7)13-11(15)9-5-6-10(18-9)14(16)17/h1-6H,(H,13,15)

InChiKey

JBIKQXOZLBLMKI-UHFFFAOYSA-N

IUPAC Name

N-(4-iodophenyl)-5-nitrofuran-2-carboxamide

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called B2341 STING Inhibitor, C-176. B2341-5 is the same size as the 5 mg size of ab285438.

Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Storage information
This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
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Product protocols

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Complementary Products

Biochemicals

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Biochemicals

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