MW 374.3 Da, Purity >98%. Potent, competitive, selective and cell-permeable inhibitor of CaM-KK (Ki values are0.21 μM and 40 nM for CaM-KKα and CaM-KKβ respectively). Potent, competitive AhR agonist (EC50 = 43 nM). Active in vivo..
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- International journal of molecular sciences 23:2022Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium Signalling Pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesParisa Vahidi Ferdowsi,Kiran D K Ahuja,Jeffrey M Beckett,Stephen MyersPubMed 35216322
- International journal of molecular sciences 21:2020Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNicholas D LeBlond et. al.PubMed 33261140
- Autophagy 17:925-9472020Induction of autophagy and suppression of type I IFN secretion by CSFV.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBaoming Xie,Mingqiu Zhao,Dan Song,Keke Wu,Lin Yi,Wenhui Li,Xiaoming Li,Kun Wang,Jinding ChenPubMed 32160078
Key facts
- CAS number
- 52029-86-4
- Purity
- > 98%
- Molecular weight
- 374.3 Da
- Molecular formula
- C21H14N2O5
- PubChem identifier
- 16760660
- Nature
- Synthetic
Target data
Alternative names
1810038L18Rik, CAMKK, CAMKK alpha protein, CAMKK beta protein, CAMKKA, CAMKKB, CK II, CK II alpha, CK II alpha', CK II beta, CK2A1, CK2A2, CK2B, CK2N, CSK21_HUMAN, CSK22_HUMAN, CSK2B_HUMAN, CSNK 2B, Ca2+/calmodulin-dependent protein kinase kinase alpha, CaM-KK 1, CaM-KK alpha, CaM-KK beta, CaM-kinase IV kinase, CaM-kinase kinase 1, CaM-kinase kinase 2, CaM-kinase kinase alpha, CaM-kinase kinase beta, Calcium/calmodulin dependent protein kinase beta, Calcium/calmodulin dependent protein kinase kinase, Calcium/calmodulin dependent protein kinase kinase 1 alpha, Calcium/calmodulin dependent protein kinase kinase 2 beta, Calcium/calmodulin-dependent protein kinase kinase 1, Calcium/calmodulin-dependent protein kinase kinase 2, Calcium/calmodulin-dependent protein kinase kinase alpha, Calcium/calmodulin-dependent protein kinase kinase beta, Casein kinase 2 alpha prime polypeptide, Casein kinase 2 beta polypeptide, Casein kinase II alpha chain, Casein kinase II alpha' chain, Casein kinase II beta subunit, Casein kinase II subunit alpha, Casein kinase II subunit alpha', Casein kinase II subunit beta, Casein kinase II, alpha 1 polypeptide, Casein kinase II, alpha 1 related sequence 4, Csnk2a1-rs4, DKFZp761M0423, DYRK2_HUMAN, Dual specificity tyrosine (Y) phosphorylation regulated kinase 2, Dual specificity tyrosine-phosphorylation-regulated kinase 2, EC 2.7.12.1, FLJ21217, FLJ21365, FLJ43934, G5A, KKCC1_HUMAN, KKCC2_HUMAN, Kid 1, Kinase induced by depolarization, MAP kinase interacting kinase 1, MAP kinase interacting serine/threonine kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine-protein kinase 1, MAPK signal integrating kinase 1, MGC102141, MGC138222, MGC138224, MGC34095, MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1, MKNK1_HUMAN, ONCOGENE PIM3, OTTHUMP00000025825, OTTMUSP00000006419, OTTMUSP00000016898;, PIM2_HUMAN, PIM3_HUMAN, Phosvitin, Pim 2 oncogene, Pim 3 oncogene, Pim-2h, Pim-3 proto-oncogene, serine/threonine kinase, Protein G5a, Protein kinase Kid 1, Proto Oncogene PIM2, Proto-oncogene Pim-2 (serine threonine kinase), RP23-452D3.3, Serine/threonine kinase PIM2, Serine/threonine kinase Pim 3, Serine/threonine-protein kinase Pim-2, Serine/threonine-protein kinase Pim-3
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MW 374.3 Da, Purity >98%. Potent, competitive, selective and cell-permeable inhibitor of CaM-KK (Ki values are0.21 μM and 40 nM for CaM-KKα and CaM-KKβ respectively). Potent, competitive AhR agonist (EC50 = 43 nM). Active in vivo..
Key facts
- CAS number
- 52029-86-4
- Purity
- > 98%
- Molecular weight
- 374.3 Da
- Molecular formula
- C21H14N2O5
- PubChem identifier
- 16760660
- Nature
- Synthetic
- Solubility
Soluble in DMSO to 25 mM.
- Biochemical name
- STO-609 acetate
- Biological description
Potent, competitive, selective and cell-permeable inhibitor of CaM-KK (Ki values are0.21 μM and 40 nM for CaM-KKα and CaM-KKβ respectively). Potent, competitive AhR agonist (EC50 = 43 nM). Active in vivo.
- Canonical SMILES
- CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
- InChI
- InChI=1S/C19H10N2O3.C2H4O2/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18;1-2(3)4/h1-9H,(H,23,24);1H3,(H,3,4)
- InChIKey
- WNRSTFUVBWNELX-UHFFFAOYSA-N
- IUPAC name
- acetic acid;11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- Ambient
- Appropriate long-term storage conditions
- Ambient
- Storage information
- The product can be stored for up to 12 months
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1 product image
Chemical Structure - STO-609 acetate, CaM-KK inhibitor (ab141591)
2D chemical structure image of ab141591, STO-609 acetate, CaM-KK inhibitor
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