JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120557

TC-2403 oxalate, alpha4beta2 nAChR selective agonist

Be the first to review this product! Submit a review

|

(1 Publication)

MW 252.27 g/mol, Purity >99%. High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC50 = 732 nM in rat thalamic synaptosomes).
1 Images
Chemical Structure - TC-2403 oxalate, alpha4beta2 nAChR selective agonist (AB120557)
  • Chemical Structure

Lab

Chemical Structure - TC-2403 oxalate, alpha4beta2 nAChR selective agonist (AB120557)

2D chemical structure image of ab120557, TC-2403 oxalate, alpha4beta2 nAChR selective agonist

Key facts

CAS number

220662-95-3

Purity

>99%

Form

Solid

form

Molecular weight

252.27 g/mol

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>4</sub>N<sub>2</sub>.C<sub>2</sub>H<sub>2</sub>O<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC50 = 732 nM in rat thalamic synaptosomes).

IUPAC Name

(E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 8:809 PubMed29167641

2017

α Nicotinic Agonist AR-R17779 Protects Mice against 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in a Spleen-Dependent Way.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Grandi,Irene Zini,Lisa Flammini,Anna M Cantoni,Valentina Vivo,Vigilio Ballabeni,Elisabetta Barocelli,Simona Bertoni
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com