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AB120889

Tenovin-1, p53 Activator

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MW 369.48 g/mol, Purity >98%. p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro.
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Chemical Structure - Tenovin-1, p53 Activator (AB120889)
  • Chemical Structure

Lab

Chemical Structure - Tenovin-1, p53 Activator (AB120889)

2D chemical structure image of ab120889, Tenovin-1, p53 Activator

Key facts

CAS number

380315-80-0

Purity

>98%

Molecular weight

369.48 g/mol

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>2</sub><sub>3</sub>N<sub>3</sub>O<sub>2</sub>S

Nature

Synthetic

Solubility

Soluble in DMSO to 0.25 mg/ml

Biological description

p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro.

Canonical smiles

CC(=O)NC1CCC(CC1)NC(=S)NC(=O)C1CCC(CC1)C(C)(C)C

IUPAC Name

N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl-4-(1,1-dimethylethyl)]benzamide

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Biochemicals

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(-)-Epigallocatechin gallate, antioxidant flavonoid

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Primary Antibodies

AB15580

Anti-Ki67 antibody

BOND RX™ Validated|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody (AB15580)

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Primary Antibodies

AB214337

Anti-Flavivirus NS1 antibody [D/2/D6/B7]

Immunocytochemistry/ Immunofluorescence - Anti-Flavivirus NS1 antibody [D/2/D6/B7] (AB214337)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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