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MW 471.7 Da, Purity >98%. K+ channel blocker (Kv11.1). Blocks ATP-sensitive K+ channels (IC50 = 1.2 μM). H1 receptor antagonist.
Alternative names=1,8-cineole 2-exo-monooxygenase, 1B07_HUMAN, 3dopamine receptor, 5 HT 2B receptor, 5 HT(2B), 5 HT2 receptor, 5 Hydroxytryptamine 2C receptor, 5 hydroxytryptamine (serotonin) receptor 2B, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine (serotonin) receptor 6 G protein coupled, 5 hydroxytryptamine 2B receptor, 5 hydroxytryptamine 6 receptor, 5-HT-1C, 5-HT-2, 5-HT-6, 5-HTR2C, 5-ht-1c receptor, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine 2A receptor, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5HT2A_HUMAN, 5HT2B_HUMAN, 5HT2C_HUMAN, 5HT2F, 5HT6R_HUMAN, A830040C14Rik, ABC member 16, MDR/TAP subfamily, ABC16, ABCB1, ABCBB_HUMAN, ADA1A_HUMAN, ADA1B_HUMAN, ADA1D_HUMAN, ADRA 1, ADRA1A, ADRA1L1, AI838772, AIS, ALPHA1AAR, AM4 7, ANDR_HUMAN, APOPAIN, AR, AR8, ARO, ARO1, AS, ATP binding cassette sub family B (MDR/TAP) member 11, ATP-binding cassette sub-family B member 11, AW493413, Adra1c, Adra1d, Adrenergic alpha 1A receptor, Adrenergic alpha 1B receptor, Adrenergic alpha 1C receptor, Adrenergic alpha 1D receptor, Adrenergic receptor alpha 1a, Adrenergic receptor alpha 1b, Adrenergic receptor alpha 1c, Adrenergic, alpha 1A , receptor variant 1, Adrenergic, alpha 1A , receptor variant 11, Adrenergic, alpha 1A , receptor variant 3, Adrenergic, alpha 1A , receptor variant 5, Adrenergic, alpha 1A , receptor variant 8, Adrenoceptor alpha 1A, Adrenoceptor alpha 1B, Albendazole monooxygenase, Albendazole sulfoxidase, Alpha 1 adrenergic receptor, Alpha adrenergic receptor 1b, Alpha adrenergic receptor 1d, Alpha-1A adrenergic receptor, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-1D adrenoceptor, Alpha-1D adrenoreceptor, Alpha-adrenergic receptor 1a, Alpha-adrenergic receptor 1c, Alpha1BAR, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Apoptotic protease Mch-3, Arachidonic acid epoxygenase, Aromatase, B-4901, B-7 alpha chain, BPHS, mouse, homolog of, BRIC2, Beta-interferon, Bile salt export pump, Bsep, C-C CKR-5, C-C chemokine receptor type 5, C-C motif chemokine receptor 5 A159A, C-mpl ligand, CAC1C_HUMAN, CAC1D_HUMAN, CAC1S_HUMAN, CACH 2, CACH1, CACH3, CACN 2, CACN1, CACN4, CACNA 1D, CACNL1A1, CACNL1A2, CACNL1A3, CAR, CAR BETA, CARA, CASP3_HUMAN, CASP7_HUMAN, CC Chemokine Receptor 5, CC3, CCHL1A1, CCHL1A2, CCHL1A3, CCR5 chemokine (C C motif) receptor 5, CCR5_HUMAN, CD 195, CD195 Antigen, CDCD2, CHEMR13, CKR 5, CMD1E, CMH-1, CMKBR 5, CMPD2, CP19A_HUMAN, CP2J2_HUMAN, CP33, CP34, CP3A4_HUMAN, CPJ2, CPP-32, CPP32B, CPV1, CYAR, CYP19, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, CYPIIJ2, CYPXIX, CaV1.2, Cach1b, Calcium channel, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle, Calcium channel L type alpha 1 polypeptide isoform 2, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit, Calcium channel neuroendocrine/brain type alpha 1 subunit, Calcium channel voltage dependent L type alpha 1, Calcium channel voltage dependent L type alpha 1C subunit, Calcium channel voltage dependent L type alpha 1D subunit, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, hypokalemic periodic paralysis, Calcium channel, skeletal muscle dihydropyridine sensitive , alpha 1 subunit, Calcium channel, voltage dependent, L type, alpha 1S subunit, Calcium channel, voltage-dependent, L type, alpha 1S subunit, b, Car 1, Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit, Casp3a, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-3, Caspase-3 subunit p12, Caspase-7 subunit p11, Cav1.1, Cav1.3, Chemokine C C motif receptor 5, Chemokine receptor CCR5, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, Cyp19a1, Cysteine protease CPP32, Cytochrome P-450AROM, Cytochrome P450 19A1, Cytochrome P450 2J2, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 2 subfamily J polypeptide 2, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450 subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2, Cytochrome P450 subfamily IIJ polypeptide 2, Cytochrome P450, family 19, subfamily A, polypeptide 1, Cytochrome P450, subfamily XIX (aromatization of androgens), Cytochrome P450-PCN1, D(1A) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, D1A dopamine receptor, D2 dopamine receptor, D2DR, D2R, DA transporter, DADR, DAT, DAT 1, DHPR alpha 1, DHPR alpha 1 subunit, DHTR, DNA replication inhibitor, DRD 1A, DRD1_HUMAN, DRD2_HUMAN, DRD3_HUMAN, Dihydro testosterone receptor, Dihydropyridine receptor, Dihydropyridine sensitive L type calcium channel alpha 1 subunit, Dihydrotestosterone receptor (DHTR), Dopamine D1 receptor, Dopamine D2 receptor, Dopamine D3 receptor, Dopamine receptor D2, Dopamine receptor D3, Dopamine transporter, Dopamine transporter 1, EC 3.4.22.56, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ESRL 1, ESRR A, ETM1, Eag-related protein 1, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen synthase, Estrogen synthetase, Estrogen-related receptor alpha, Estrra, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, FET1, FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FLJ11090, FLJ44809, FLJ78003, FRAP, FRAP1, FRAP2, Fibroblast interferon, G protein coupled receptor, GEMI_HUMAN, GMNN, Geminin, Geminin DNA replication inhibitor, Glucocorticoid inducible P450, H-ERG, H1 R, HB 1, HB2, HBBD, HC class I antigen SHCHA, HH1, HH1R, HIV-1 fusion coreceptor, HLA class I histocompatibility antigen, HLA class I histocompatibility antigen, B alpha chain, HLA-B histocompatibility type, HLP, HOKPP, HRH1_HUMAN, HTR 2, HTR 2A, HTR 6, HTR2, formerly, HTR2C, HUMARA, HYSP1, HisH1, Histamine H(1) receptor, Histamine H1 receptor, Histamine receptor H1, Histamine receptor subclass H1, Htr 2b, Htr1c, HypoPP, ICCD, ICE-LAP3, ICE-like apoptotic protease 3, ICE3, IDDM22, IFB, IFF, IFN-beta, IFNB 1, IFNB_HUMAN, IVF, Interferon beta, Interferon beta 1 fibroblast, Interferon beta precursor, KCNH2_HUMAN, KD, Kennedy disease (KD), Kv11.1, L type, LICE, LICE2, LQT 2, LQT3, LQT8, MB67, MCH3, MGC104252, MGC104309, MGC112732, MGC126680, MGC163194, MGC96956, MGC97144, MGDF, MHC Class I HLA heavy chain, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC class 1 antigen, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I molecule, MHC class I-antigen B*7, MHS5, MIP-1 alpha receptor, MKCSF, MPL ligand, MPLLG, MTOR_HUMAN, Malignant hyperthermia susceptibility 5, Mammalian target of rapamycin, Mechanistic target of rapamycin, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Megakaryocyte stimulating factor, Microsomal monooxygenase, Myeloproliferative leukemia virus oncogene ligand, NF 25, NK-2 receptor, NK2R_HUMAN, NKNAR, NP75 protein, NR1I3_HUMAN, NR3B1, NR3C4, Neurokinin 2 receptor, Neurokinin A receptor, Neurotransmitter transporter, Nifedipine oxidase, Norepinephrine transporter, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), OTTHUMP00000001983, OTTHUMP00000010550, OTTHUMP00000039393, OTTHUMP00000162543, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, OTTHUMP00000198350, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, P 450AROM, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, PARP cleavage protease, PASNA, PFHB1, PFIC 2, PGY4, PKDYS, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, Prepro thrombopoietin, Procaspase3, Protein Yama, Quinine 3-monooxygenase, RAFT1, RAPT1, ROB1, RP24-311F12.2, RP3 369A17.3, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein, Rapamycin target protein 1, SANDD, SBMA, SC6A2_HUMAN, SC6A3_HUMAN, SCA-1, SCAN1, SCN5A_HUMAN, SEROTONIN 5HT2B RECEPTOR, SKR, SLC6A3, SLC6A5, SMAX1, SPDA1, SQT1, SREBP cleavage activity 1, SSS1, Scn5a (gene name), Serine/threonine-protein kinase mTOR, Serotonin 5-HT-2C receptor, Serotonin receptor 2A, Serotonin receptor 2B, Serotonin receptor 2C, Serotonin receptor 6, Seven transmembrane helix receptor, Sister of P glycoprotein, Slc6a2, Sodium channel protein cardiac muscle alpha subunit, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V alpha subunit, Sodium channel protein type V subunit alpha, Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, Solute carrier family 6 (neurotransmitter transporter dopamine), member 3, Solute carrier family 6 (neurotransmitter transporter norepinephrine) member 5, Solute carrier family 6 (neurotransmitter transporter), member 3, Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, Solute carrier family 6 member 2, Solute carrier family 6 member 3, Solute carrier family 6 member 5, Spgp, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid hormone receptor ERR1, Stomach fundus serotonin receptor, Substance-K receptor, TAC 2R, TAC R2, TACR 2, TACR2, TFM, THCYT1, THPO, TPO_HUMAN, TS, TTPP1, TYDP, TYDP1_HUMAN, Tachykinin receptor 2, Tachykinin receptor 2 (substance K receptor; neurokinin 2 receptor), Taurochenodeoxycholate 6-alpha-hydroxylase, Testicular Feminization (TFM), Thrombopoietin, Thrombopoietin nirs variant 1, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, VF1, Variable number tandem repeat (VNTR), Voltage dependent L type calcium channel alpha 1C subunit, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, Voltage gated calcium channel alpha 1 subunit, Voltage gated calcium channel alpha subunit Cav1.2, Voltage gated calcium channel alpha subunit Cav1.3, Voltage gated potassium channel, subfamily H, member 2, Voltage gated sodium channel alpha subunit Nav1.5, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-gated calcium channel subunit alpha Cav1.1, Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3, Voltage-gated potassium channel subunit Kv11.1, Voltage-gated sodium channel subunit alpha Nav1.5, Yama, Yama protein, alpha-1 polypeptide, androgen receptor splice variant 4b, cardiac muscle, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1), dopamine receptor D1, eag homolog, estrogen receptor related receptor alpha, flavoprotein-linked monooxygenase, fmd, hERG-1, hERR1, isoform 1, isoform 2, isoform 3, leukocyte antigen class I-B, major histocompatibility complex, class I, B, mldy, orphan nuclear hormone receptor, progressive familial intrahepatic cholestasis 2, serotonin 1c receptor, serotonin 2c receptor, serotonin 5-HT-2 receptor, formerly, serotonin 5-HT-2A receptor, sj
50679-08-8
> 98%
Solid
471.7 Da
C32H41NO2
5405
Synthetic
MW 471.7 Da, Purity >98%. K+ channel blocker (Kv11.1). Blocks ATP-sensitive K+ channels (IC50 = 1.2 μM). H1 receptor antagonist.
Alternative names=1,8-cineole 2-exo-monooxygenase, 1B07_HUMAN, 3dopamine receptor, 5 HT 2B receptor, 5 HT(2B), 5 HT2 receptor, 5 Hydroxytryptamine 2C receptor, 5 hydroxytryptamine (serotonin) receptor 2B, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine (serotonin) receptor 6 G protein coupled, 5 hydroxytryptamine 2B receptor, 5 hydroxytryptamine 6 receptor, 5-HT-1C, 5-HT-2, 5-HT-6, 5-HTR2C, 5-ht-1c receptor, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine 2A receptor, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5HT2A_HUMAN, 5HT2B_HUMAN, 5HT2C_HUMAN, 5HT2F, 5HT6R_HUMAN, A830040C14Rik, ABC member 16, MDR/TAP subfamily, ABC16, ABCB1, ABCBB_HUMAN, ADA1A_HUMAN, ADA1B_HUMAN, ADA1D_HUMAN, ADRA 1, ADRA1A, ADRA1L1, AI838772, AIS, ALPHA1AAR, AM4 7, ANDR_HUMAN, APOPAIN, AR, AR8, ARO, ARO1, AS, ATP binding cassette sub family B (MDR/TAP) member 11, ATP-binding cassette sub-family B member 11, AW493413, Adra1c, Adra1d, Adrenergic alpha 1A receptor, Adrenergic alpha 1B receptor, Adrenergic alpha 1C receptor, Adrenergic alpha 1D receptor, Adrenergic receptor alpha 1a, Adrenergic receptor alpha 1b, Adrenergic receptor alpha 1c, Adrenergic, alpha 1A , receptor variant 1, Adrenergic, alpha 1A , receptor variant 11, Adrenergic, alpha 1A , receptor variant 3, Adrenergic, alpha 1A , receptor variant 5, Adrenergic, alpha 1A , receptor variant 8, Adrenoceptor alpha 1A, Adrenoceptor alpha 1B, Albendazole monooxygenase, Albendazole sulfoxidase, Alpha 1 adrenergic receptor, Alpha adrenergic receptor 1b, Alpha adrenergic receptor 1d, Alpha-1A adrenergic receptor, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-1D adrenoceptor, Alpha-1D adrenoreceptor, Alpha-adrenergic receptor 1a, Alpha-adrenergic receptor 1c, Alpha1BAR, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Apoptotic protease Mch-3, Arachidonic acid epoxygenase, Aromatase, B-4901, B-7 alpha chain, BPHS, mouse, homolog of, BRIC2, Beta-interferon, Bile salt export pump, Bsep, C-C CKR-5, C-C chemokine receptor type 5, C-C motif chemokine receptor 5 A159A, C-mpl ligand, CAC1C_HUMAN, CAC1D_HUMAN, CAC1S_HUMAN, CACH 2, CACH1, CACH3, CACN 2, CACN1, CACN4, CACNA 1D, CACNL1A1, CACNL1A2, CACNL1A3, CAR, CAR BETA, CARA, CASP3_HUMAN, CASP7_HUMAN, CC Chemokine Receptor 5, CC3, CCHL1A1, CCHL1A2, CCHL1A3, CCR5 chemokine (C C motif) receptor 5, CCR5_HUMAN, CD 195, CD195 Antigen, CDCD2, CHEMR13, CKR 5, CMD1E, CMH-1, CMKBR 5, CMPD2, CP19A_HUMAN, CP2J2_HUMAN, CP33, CP34, CP3A4_HUMAN, CPJ2, CPP-32, CPP32B, CPV1, CYAR, CYP19, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, CYPIIJ2, CYPXIX, CaV1.2, Cach1b, Calcium channel, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle, Calcium channel L type alpha 1 polypeptide isoform 2, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit, Calcium channel neuroendocrine/brain type alpha 1 subunit, Calcium channel voltage dependent L type alpha 1, Calcium channel voltage dependent L type alpha 1C subunit, Calcium channel voltage dependent L type alpha 1D subunit, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, hypokalemic periodic paralysis, Calcium channel, skeletal muscle dihydropyridine sensitive , alpha 1 subunit, Calcium channel, voltage dependent, L type, alpha 1S subunit, Calcium channel, voltage-dependent, L type, alpha 1S subunit, b, Car 1, Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit, Casp3a, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-3, Caspase-3 subunit p12, Caspase-7 subunit p11, Cav1.1, Cav1.3, Chemokine C C motif receptor 5, Chemokine receptor CCR5, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, Cyp19a1, Cysteine protease CPP32, Cytochrome P-450AROM, Cytochrome P450 19A1, Cytochrome P450 2J2, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 2 subfamily J polypeptide 2, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450 subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2, Cytochrome P450 subfamily IIJ polypeptide 2, Cytochrome P450, family 19, subfamily A, polypeptide 1, Cytochrome P450, subfamily XIX (aromatization of androgens), Cytochrome P450-PCN1, D(1A) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, D1A dopamine receptor, D2 dopamine receptor, D2DR, D2R, DA transporter, DADR, DAT, DAT 1, DHPR alpha 1, DHPR alpha 1 subunit, DHTR, DNA replication inhibitor, DRD 1A, DRD1_HUMAN, DRD2_HUMAN, DRD3_HUMAN, Dihydro testosterone receptor, Dihydropyridine receptor, Dihydropyridine sensitive L type calcium channel alpha 1 subunit, Dihydrotestosterone receptor (DHTR), Dopamine D1 receptor, Dopamine D2 receptor, Dopamine D3 receptor, Dopamine receptor D2, Dopamine receptor D3, Dopamine transporter, Dopamine transporter 1, EC 3.4.22.56, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ESRL 1, ESRR A, ETM1, Eag-related protein 1, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen synthase, Estrogen synthetase, Estrogen-related receptor alpha, Estrra, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, FET1, FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FLJ11090, FLJ44809, FLJ78003, FRAP, FRAP1, FRAP2, Fibroblast interferon, G protein coupled receptor, GEMI_HUMAN, GMNN, Geminin, Geminin DNA replication inhibitor, Glucocorticoid inducible P450, H-ERG, H1 R, HB 1, HB2, HBBD, HC class I antigen SHCHA, HH1, HH1R, HIV-1 fusion coreceptor, HLA class I histocompatibility antigen, HLA class I histocompatibility antigen, B alpha chain, HLA-B histocompatibility type, HLP, HOKPP, HRH1_HUMAN, HTR 2, HTR 2A, HTR 6, HTR2, formerly, HTR2C, HUMARA, HYSP1, HisH1, Histamine H(1) receptor, Histamine H1 receptor, Histamine receptor H1, Histamine receptor subclass H1, Htr 2b, Htr1c, HypoPP, ICCD, ICE-LAP3, ICE-like apoptotic protease 3, ICE3, IDDM22, IFB, IFF, IFN-beta, IFNB 1, IFNB_HUMAN, IVF, Interferon beta, Interferon beta 1 fibroblast, Interferon beta precursor, KCNH2_HUMAN, KD, Kennedy disease (KD), Kv11.1, L type, LICE, LICE2, LQT 2, LQT3, LQT8, MB67, MCH3, MGC104252, MGC104309, MGC112732, MGC126680, MGC163194, MGC96956, MGC97144, MGDF, MHC Class I HLA heavy chain, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC class 1 antigen, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I molecule, MHC class I-antigen B*7, MHS5, MIP-1 alpha receptor, MKCSF, MPL ligand, MPLLG, MTOR_HUMAN, Malignant hyperthermia susceptibility 5, Mammalian target of rapamycin, Mechanistic target of rapamycin, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Megakaryocyte stimulating factor, Microsomal monooxygenase, Myeloproliferative leukemia virus oncogene ligand, NF 25, NK-2 receptor, NK2R_HUMAN, NKNAR, NP75 protein, NR1I3_HUMAN, NR3B1, NR3C4, Neurokinin 2 receptor, Neurokinin A receptor, Neurotransmitter transporter, Nifedipine oxidase, Norepinephrine transporter, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), OTTHUMP00000001983, OTTHUMP00000010550, OTTHUMP00000039393, OTTHUMP00000162543, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, OTTHUMP00000198350, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, P 450AROM, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, PARP cleavage protease, PASNA, PFHB1, PFIC 2, PGY4, PKDYS, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, Prepro thrombopoietin, Procaspase3, Protein Yama, Quinine 3-monooxygenase, RAFT1, RAPT1, ROB1, RP24-311F12.2, RP3 369A17.3, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein, Rapamycin target protein 1, SANDD, SBMA, SC6A2_HUMAN, SC6A3_HUMAN, SCA-1, SCAN1, SCN5A_HUMAN, SEROTONIN 5HT2B RECEPTOR, SKR, SLC6A3, SLC6A5, SMAX1, SPDA1, SQT1, SREBP cleavage activity 1, SSS1, Scn5a (gene name), Serine/threonine-protein kinase mTOR, Serotonin 5-HT-2C receptor, Serotonin receptor 2A, Serotonin receptor 2B, Serotonin receptor 2C, Serotonin receptor 6, Seven transmembrane helix receptor, Sister of P glycoprotein, Slc6a2, Sodium channel protein cardiac muscle alpha subunit, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V alpha subunit, Sodium channel protein type V subunit alpha, Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, Solute carrier family 6 (neurotransmitter transporter dopamine), member 3, Solute carrier family 6 (neurotransmitter transporter norepinephrine) member 5, Solute carrier family 6 (neurotransmitter transporter), member 3, Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, Solute carrier family 6 member 2, Solute carrier family 6 member 3, Solute carrier family 6 member 5, Spgp, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid hormone receptor ERR1, Stomach fundus serotonin receptor, Substance-K receptor, TAC 2R, TAC R2, TACR 2, TACR2, TFM, THCYT1, THPO, TPO_HUMAN, TS, TTPP1, TYDP, TYDP1_HUMAN, Tachykinin receptor 2, Tachykinin receptor 2 (substance K receptor; neurokinin 2 receptor), Taurochenodeoxycholate 6-alpha-hydroxylase, Testicular Feminization (TFM), Thrombopoietin, Thrombopoietin nirs variant 1, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, VF1, Variable number tandem repeat (VNTR), Voltage dependent L type calcium channel alpha 1C subunit, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, Voltage gated calcium channel alpha 1 subunit, Voltage gated calcium channel alpha subunit Cav1.2, Voltage gated calcium channel alpha subunit Cav1.3, Voltage gated potassium channel, subfamily H, member 2, Voltage gated sodium channel alpha subunit Nav1.5, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-gated calcium channel subunit alpha Cav1.1, Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3, Voltage-gated potassium channel subunit Kv11.1, Voltage-gated sodium channel subunit alpha Nav1.5, Yama, Yama protein, alpha-1 polypeptide, androgen receptor splice variant 4b, cardiac muscle, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1), dopamine receptor D1, eag homolog, estrogen receptor related receptor alpha, flavoprotein-linked monooxygenase, fmd, hERG-1, hERR1, isoform 1, isoform 2, isoform 3, leukocyte antigen class I-B, major histocompatibility complex, class I, B, mldy, orphan nuclear hormone receptor, progressive familial intrahepatic cholestasis 2, serotonin 1c receptor, serotonin 2c receptor, serotonin 5-HT-2 receptor, formerly, serotonin 5-HT-2A receptor, sj
50679-08-8
> 98%
Solid
471.7 Da
C32H41NO2
5405
Synthetic
Solubility at 30 °C (g/100 ml): ethanol 3.780; methanol 3.750; hexane 0.034; 0.1M HCl 0.012; 00.1M citric acid 0.110; 0.1M tartaric acid 0.045. In water, 9.63X10-2 mg/L at 25 °C.
Terfenadine
K+ channel blocker (Kv11.1). Blocks ATP-sensitive K+ channels (IC50 = 1.2 μM). H1 receptor antagonist.
CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O
InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3
GUGOEEXESWIERI-UHFFFAOYSA-N
1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
Ambient - Can Ship with Ice
+4°C
The product can be stored for up to 12 months
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