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AB144369

Terrein, Akt and ERK inhibitor

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MW 154.16 Da, Purity >98%. Bioactive fungal metabolite. Akt and ERK inhibitor. Blocks NFκB activation. Induces G2/M cell cycle arrest. Inhibits melanogenesis. Shows antiproliferative and anti-inflammatory effects.
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Chemical Structure - Terrein, Akt and ERK inhibitor (AB144369)
  • Chemical Structure

Lab

Chemical Structure - Terrein, Akt and ERK inhibitor (AB144369)

2D chemical structure image of ab144369, Terrein, Akt and ERK inhibitor

Key facts

CAS number

582-46-7

Purity

>98%

Form

Solid

form

Source

Aspergillus terreus

Molecular weight

154.16 Da

Molecular formula

C<sub>8</sub>H<sub>1</sub><sub>0</sub>O<sub>3</sub>

PubChem

6436830

Nature

Native

Solubility

Soluble in DMSO

Biochemical name

Terrein

Biological description

Bioactive fungal metabolite. Akt and ERK inhibitor. Blocks NFκB activation. Induces G2/M cell cycle arrest. Inhibits melanogenesis. Shows antiproliferative and anti-inflammatory effects.

Canonical smiles

CC=CC1=CC(=O)C(C1O)O

Isomeric smiles

C/C=C/C1=CC(=O)[C@@H]([C@H]1O)O

InChi

InChI=1S/C8H10O3/c1-2-3-5-4-6(9)8(11)7(5)10/h2-4,7-8,10-11H,1H3/b3-2+/t7-,8-/m0/s1

InChiKey

MHOOPNKRBMHHEC-HZIBQTDNSA-N

IUPAC Name

(4S,5R)-4,5-dihydroxy-3-[(E)-prop-1-enyl]cyclopent-2-en-1-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

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