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AB146166

Tetrabenazine, VMAT2 inhibitor

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MW 317.42 g/mol. Potent, reversible VMAT2 inhibitor (IC50 = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active.
1 Images
Chemical Structure - Tetrabenazine, VMAT2 inhibitor (AB146166)
  • Chemical Structure

Lab

Chemical Structure - Tetrabenazine, VMAT2 inhibitor (AB146166)

2D chemical structure image of ab146166, Tetrabenazine, VMAT2 inhibitor

Key facts

CAS number

58-46-8

Form

Solid

form

Molecular weight

317.42 g/mol

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>7</sub>NO<sub>3</sub>

Nature

Synthetic

Biological description

Potent, reversible VMAT2 inhibitor (IC50 = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active.

Canonical smiles

CC(C)CC2CN3CCC1CC(OC)C(OC)CC1C3CC2=O

InChi

InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3

InChiKey

MKJIEFSOBYUXJB-UHFFFAOYSA-N

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Biochemicals

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Reserpine, Irreversible vesicular monoamine transporter antagonist

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Proteins & Peptides

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Primary Antibodies

AB105459

Anti-WIPI2 antibody [2A2]

BOND RX™ Validated|KO Validated|Trial Size

Western blot - Anti-WIPI2 antibody [2A2] (AB105459)

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Primary Antibodies

AB26

Anti-p53 antibody [PAb 240]

KO Validated|Lab Essentials

Western blot - Anti-p53 antibody [PAb 240] (AB26)

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