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AB275547

Tetramethylrhodamine, methyl ester (TMRM)

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(3 Publications)

MW 436.93 g/mol, Purity >95%. Fluorescent, cell-permeant cationic dye for measuring mitochondrial membrane potential. Accumulates in healthy, negatively charged mitochondria. Exhibits re-orange fluorscence (Em = 573 nm). Minimal fluorescence observed when mitochondrial membrane potential collapses. Used to monitor cell health and viability. Stained cells can be analysed via flow cytometry, fluorescence microscopy or fluorescence plate reader techniques..
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Chemical Structure - Tetramethylrhodamine, methyl ester (TMRM) (AB275547)
  • Chemical Structure

Lab

Chemical Structure - Tetramethylrhodamine, methyl ester (TMRM) (AB275547)

Chemical structure of Tetramethylrhodamine, methyl ester (TMRM), 115532-49-5

Key facts

CAS number

152842-32-5

Purity

>95%

Form

Solid

form

Molecular weight

436.93 g/mol

Molecular formula

C<sub>2</sub><sub>5</sub>H<sub>2</sub><sub>5</sub>ClN<sub>2</sub>O<sub>3</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Soluble in ethanol

Biological description

Fluorescent, cell-permeant cationic dye for measuring mitochondrial membrane potential. Accumulates in healthy, negatively charged mitochondria. Exhibits re-orange fluorscence (Em = 573 nm). Minimal fluorescence observed when mitochondrial membrane potential collapses. Used to monitor cell health and viability. Stained cells can be analysed via flow cytometry, fluorescence microscopy or fluorescence plate reader techniques.

Excitation/Emission

Ex: 548nm, Em: 573nm

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark|Store under desiccating conditions
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Brain : a journal of neurology 146:4378-4394 PubMed37070763

2023

Glucocorticoid-driven mitochondrial damage stimulates Tau pathology.

Applications

Unspecified application

Species

Unspecified reactive species

Fang Du,Qing Yu,Russell H Swerdlow,Clarissa L Waites

NPJ precision oncology 6:90 PubMed36456699

2022

Microfluidic-based dynamic BH3 profiling predicts anticancer treatment efficacy.

Applications

Unspecified application

Species

Unspecified reactive species

Albert Manzano-Muñoz,José Yeste,María A Ortega,Fernando Martín,Anna López,Jordi Rosell,Sandra Castro,César Serrano,Josep Samitier,Javier Ramón-Azcón,Joan Montero

Nutrients 14: PubMed36014880

2022

Water-Soluble Tomato Concentrate, a Potential Antioxidant Supplement, Can Attenuate Platelet Apoptosis and Oxidative Stress in Healthy Middle-Aged and Elderly Adults: A Randomized, Double-Blinded, Crossover Clinical Trial.

Applications

Unspecified application

Species

Unspecified reactive species

Zezhong Tian,Kongyao Li,Die Fan,Xiaoli Gao,Xilin Ma,Yimin Zhao,Dan Zhao,Ying Liang,Qiuhua Ji,Yiting Chen,Yan Yang
View all publications
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