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AB146345

Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye

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(20 Publications)

MW 414.3 Da, Purity >98%. Achieve your results faster with highly validated, pure and trusted compounds.
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Functional Studies - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)
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PubMed

Functional Studies - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)

NaHS protects viability of HEI-OC1 cells upon gentamicin toxicity.

Gentamicin (GM) was added to the culture medium to a concentration of 0 (control), 1, 2.5 and 5 mM respectively incubated for 48 hours. Representative culture images (A) and viability measured by MTT assay (B) of HEI-OC1 cell culture after gentamicin (GM) treatment were shown.

Scale bar 100 μm. Values were represented as the mean ± SEM from three independent experiments. * P < 0.05 vs control.

(After Figure 1A & B of Dong et al).

Dong et al PLoS One. 2015; 10(8): e0136051. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

Chemical Structure - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)
  • Chemical Structure

Lab

Chemical Structure - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)

2D chemical structure image of ab146345, Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye

Key facts

CAS number

298-93-1

Purity

>98%

Form

Solid

form

Molecular weight

414.3 Da

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>1</sub><sub>6</sub>BrN<sub>5</sub>S

PubChem

64965

Nature

Synthetic

Biochemical name

Thiazolyl blue

Canonical smiles

CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

InChi

InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

IUPAC Name

2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide

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Secondary Antibodies

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Assay Kits

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (20)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 8:791 PubMed40410544

2025

Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs against RNA viruses.

Applications

Unspecified application

Species

Unspecified reactive species

Alina Renz,Mirjam Hohner,Raphaël Jami,Maximilian Breitenbach,Jonathan Josephs-Spaulding,Johanna Dürrwald,Lena Best,Victoria Dulière,Chloé Mialon,Stefanie M Bader,Georgios Marinos,Nantia Leonidou,Filipe Cabreiro,Marc Pellegrini,Marcel Doerflinger,Manuel Rosa-Calatrava,Andrés Pizzorno,Andreas Dräger,Michael Schindler,Christoph Kaleta

International journal of molecular sciences 25: PubMed38203785

2024

Propolis Protects GC-1spg Spermatogonial Cells against Tert-Butyl Hydroperoxide-Induced Oxidative Damage.

Applications

Unspecified application

Species

Unspecified reactive species

Filipa Duarte,Mariana Feijó,Ângelo Luís,Sílvia Socorro,Cláudio J Maia,Sara Correia

EMBO molecular medicine 15:e17761 PubMed37807968

2023

NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5.

Applications

Unspecified application

Species

Unspecified reactive species

Selina Gurri,Beat Siegenthaler,Michael Cangkrama,Gaetana Restivo,Marcel Huber,James Saliba,Reinhard Dummer,Volker Blank,Daniel Hohl,Sabine Werner

Biomedical reports 19:83 PubMed37881601

2023

Antiproliferative activity and apoptosis‑inducing effects of polysaccharides against human breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Budi Kurniawan,Wichanee Bankeeree,Pattamawadee Yanatatsaneejit,Sehanat Prasongsuk

PLoS biology 20:e3001683 PubMed35853000

2022

Alternative splicing of METTL3 explains apparently METTL3-independent m6A modifications in mRNA.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Xian Poh,Aashiq H Mirza,Brian F Pickering,Samie R Jaffrey

PloS one 17:e0265084 PubMed35263366

2022

Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2'-deoxyuridine (FUdR).

Applications

Unspecified application

Species

Unspecified reactive species

Heiko M Lesslich,Lars Klapal,Justus Wilke,Annika Haak,Irmgard D Dietzel

Cells 11: PubMed35053376

2022

Lipocalin-2 (LCN2) Deficiency Leads to Cellular Changes in Highly Metastatic Human Prostate Cancer Cell Line PC-3.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah K Schröder,Manuela Pinoé-Schmidt,Ralf Weiskirchen

Heliyon 7:e07888 PubMed34522800

2021

Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™.

Applications

Unspecified application

Species

Unspecified reactive species

Raphael Serruya,Yehoshua Maor

Materials (Basel, Switzerland) 14: PubMed34070481

2021

Refractory Metal Coated Alumina Foams as Support Material for Stem Cell and Fibroblasts Cultivation.

Applications

Unspecified application

Species

Unspecified reactive species

Georg Hasemann,Ulf Betke,Manja Krüger,Heike Walles,Michael Scheffler

Scientific reports 11:8967 PubMed33903679

2021

The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Olivia Jones,Xiaoqian Cheng,Saravana R K Murthy,Lawan Ly,Taisen Zhuang,Giacomo Basadonna,Michael Keidar,Jerome Canady
View all publications
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