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AB146618

Thiazovivin (DMSO solution), Rho kinase inhibitor

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MW 311.4 Da, Purity >95%. Rho kinase inhibitor. Thiazovivin (ab142081) solution. Reverses Ang II-induced MYPT1 and MLC phosphorylation. Enhances fibroblast reprogramming efficiency during pluripotent stem cell formation.
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Chemical Structure - Thiazovivin (DMSO solution), Rho kinase inhibitor (AB146618)
  • Chemical Structure

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Chemical Structure - Thiazovivin (DMSO solution), Rho kinase inhibitor (AB146618)

2D chemical structure image of ab146618, Thiazovivin (DMSO solution), Rho kinase inhibitor

Key facts

CAS number

1226056-71-8

Purity

>95%

Form

Liquid

form

Molecular weight

311.4 Da

Molecular formula

C<sub>1</sub><sub>5</sub>H<sub>1</sub><sub>3</sub>N<sub>5</sub>OS

PubChem

46209426

Nature

Synthetic

Biochemical name

N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide

Biological description

Rho kinase inhibitor. Thiazovivin (ab142081) solution. Reverses Ang II-induced MYPT1 and MLC phosphorylation. Enhances fibroblast reprogramming efficiency during pluripotent stem cell formation.

Canonical smiles

C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3

InChi

InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)

InChiKey

DOBKQCZBPPCLEG-UHFFFAOYSA-N

IUPAC Name

N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1736 EZSolution™ Thiazovivin. 1736-1 is the same size as the 1 mg size of ab146618.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark|Store under desiccating conditions|This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
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Product protocols

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