JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB142081

Thiazovivin, ROCK inhibitor

Be the first to review this product! Submit a review

|

(0 Publication)

MW 311.4 Da, Purity >98%. Rho kinase inhibitor. Thiazovivin (ab142081) solution. Reverses Ang II-induced MYPT1 and MLC phosphorylation. Enhances fibroblast reprogramming efficiency during pluripotent stem cell formation.
1 Images
Chemical Structure - Thiazovivin, ROCK inhibitor (AB142081)
  • Chemical Structure

Lab

Chemical Structure - Thiazovivin, ROCK inhibitor (AB142081)

2D chemical structure image of ab142081, Thiazovivin, ROCK inhibitor

Key facts

CAS number

1226056-71-8

Purity

>98%

Form

Solid

form

Molecular weight

311.4 Da

Molecular formula

C<sub>1</sub><sub>5</sub>H<sub>1</sub><sub>3</sub>N<sub>5</sub>OS

PubChem

46209426

Nature

Synthetic

Biochemical name

N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide

Biological description

Rho kinase inhibitor. Thiazovivin (ab142081) solution. Reverses Ang II-induced MYPT1 and MLC phosphorylation. Enhances fibroblast reprogramming efficiency during pluripotent stem cell formation.

Canonical smiles

C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3

InChi

InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)

InChiKey

DOBKQCZBPPCLEG-UHFFFAOYSA-N

IUPAC Name

N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide

style
left-column

Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1681 Thiazovivin. 1681-5 is the same size as the 5 mg size of ab142081.
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Complementary Products

Biochemicals

AB143784

N-Boc-Y-27632, Rho kinase (ROCK) inhibitor

Chemical Structure - N-Boc-Y-27632, Rho kinase (ROCK) inhibitor (AB143784)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Secondary Antibodies

AB191866

VHH Single Domain Anti-Rabbit IgG Fc (HRP)

Recombinant

Western blot - VHH Single Domain Anti-Rabbit IgG Fc (HRP) (AB191866)

  • 5
  • 2
Biochemicals

AB146262

Nitrotetrazolium blue chloride (NBT), Chromogenic substrate

Chemical Structure - Nitrotetrazolium blue chloride (NBT), Chromogenic substrate (AB146262)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com