Tramiprosate, Binds soluble amyloid-beta
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(2 Publications)
MW 139.18 Da. Binds soluble amyloid-β. Antifibrillogenic activity in vitro and in vivo. Sulfated glycosaminoglycan (sGAG) mimetic. Inhibits amyloid-β induced neuronal cytotoxicity. A synthetic GABA analog. Blood-brain barrier permeable and orally active.
View Alternative Names
AW061132, B230208N19Rik, BcDNA:GH07312, CAE 2, CG6706, CT20836, D Gaba2, ECA 2, ECA4, ECA5, EIEE19, EJM, EJM5, FLJ36928, FLJ92613, G-protein coupled receptor 51, GAA 5, GAB B R2, GABA, GABA A, GABA A Receptor alpha 3, GABA A Receptor alpha 6 polypeptide, GABA A receptor alpha 6, GABA A receptor subunit alpha 6, GABA alpha receptor beta-2 subunit, GABA subunit A receptor alpha 6, GABA(A) receptor, GABA(A) receptor beta 1, GABA(A) receptor beta 2, GABA(A) receptor gamma 2, GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-3, GABA(A) receptor subunit alpha-4, GABA(A) receptor subunit alpha-5, GABA(A) receptor subunit alpha-6, GABA(A) receptor subunit beta-1, GABA(A) receptor subunit beta-2, GABA(A) receptor subunit beta-3, GABA(A) receptor subunit delta, GABA(A) receptor subunit gamma-1, GABA(A) receptor subunit gamma-2, GABA(A) receptor subunit gamma-3, GABA(A) receptor subunit pi, GABA(A) receptor, alpha 1, GABA-A receptor, beta-1 polypeptide, GABA-A receptor, beta-2 polypeptide, GABA-B receptor 1, GABA-B receptor 2, GABA-B-R1, GABA-B-R2, GABAA receptor beta 3 subunit, GABAA receptor subunit beta 3, GABAB subunit 1c, GABBR1, GABBR1 3, GABR A3, GABR B3, GABR G3, GABR1_HUMAN, GABR2_HUMAN, GABRA 1, GABRA 5, GABRA 6, GABRB2, GABRG 1, GABRG 2, GABRP, GARB1, GBRA1_HUMAN, GBRA3_HUMAN, GBRA4_HUMAN, GBRA5_HUMAN, GBRA6_HUMAN, GBRB1_HUMAN, GBRB2_HUMAN, GBRB3_HUMAN, GBRD_HUMAN, GBRG1_HUMAN, GBRG2_HUMAN, GBRG3_HUMAN, GBRP_HUMAN, GC138184, GEFSP 3, GH07312, GPR 51, GPRC 3B, GPRC3A, Gaba receptor alpha 1 polypeptide, GabaA/BZ, Gamma Aminobutyric Acid A Receptor Beta 1, Gamma Aminobutyric Acid Receptor , beta-1, Gamma aminobutyric acid (GABA A) receptor subunit gamma 1, Gamma aminobutyric acid (GABA) A receptor alpha 1, Gamma aminobutyric acid (GABA) A receptor alpha 3, Gamma aminobutyric acid (GABA) A receptor alpha 4, Gamma aminobutyric acid (GABA) A receptor beta 1, Gamma aminobutyric acid (GABA) A receptor beta 3, Gamma aminobutyric acid (GABA) A receptor gamma 2, Gamma aminobutyric acid (GABA) A receptor gamma 3, Gamma aminobutyric acid (GABA) A receptor pi, Gamma aminobutyric acid (GABA) A receptor, beta 2, Gamma aminobutyric acid (GABA) B receptor 1, Gamma aminobutyric acid A receptor alpha 1, Gamma aminobutyric acid A receptor alpha 3, Gamma aminobutyric acid A receptor alpha 4, Gamma aminobutyric acid A receptor alpha 6, Gamma aminobutyric acid A receptor beta 2, Gamma aminobutyric acid A receptor gamma 2, Gamma aminobutyric acid A receptor gamma 3, Gamma aminobutyric acid A receptor pi, Gamma aminobutyric acid A receptor, gamma 1, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA A receptor alpha 5, Gamma aminobutyric acid GABA A receptor alpha 5 precursor, Gamma aminobutyric acid GABA A receptor alpha 6, Gamma aminobutyric acid GABA A receptor delta, Gamma aminobutyric acid GABA B receptor 2, Gamma aminobutyric acid receptor alpha 4 subunit, Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor, Gamma aminobutyric acid receptor delta subunit precursor GABA A receptor, Gamma aminobutyric acid receptor gamma 2 subunit, Gamma aminobutyric acid receptor pi subunit, Gamma aminobutyric acid type A receptor alpha1 subunit, Gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-3, Gamma-aminobutyric acid receptor subunit alpha-4, Gamma-aminobutyric acid receptor subunit alpha-5, Gamma-aminobutyric acid receptor subunit alpha-6, Gamma-aminobutyric acid receptor subunit beta-1, Gamma-aminobutyric acid receptor subunit beta-3, Gamma-aminobutyric acid receptor subunit delta, Gamma-aminobutyric acid receptor subunit gamma-1, Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid receptor subunit gamma-3, Gamma-aminobutyric acid receptor subunit pi, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric-acid receptor subunit beta-2, Gb 2, Gb1, HG 20, HRIHFB2099, MGC116903, MGC116904, MGC126386, MGC126387, MGC33793, MGC45284, MGC9051, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, Seven transmembrane helix receptor, dJ271M21.1.1, dJ271M21.1.2
- Chemical Structure
Lab
Chemical Structure - Tramiprosate, Binds soluble amyloid-beta (AB141116)
2D chemical structure image of ab141116, Tramiprosate, Binds soluble amyloid-beta
Properties and storage information
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Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Handling instructions
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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Refer to SDS for further information.
Publications (2)
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International journal of molecular sciences 26: PubMed40332390
2025
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Unspecified application
Species
Unspecified reactive species
International journal of molecular sciences 25: PubMed38732141
2024
Applications
Unspecified application
Species
Unspecified reactive species
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