Tranilast, Anti-inflammatory agent
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(1 Publication)
- FuncS
Unknown
Functional Studies - Tranilast, Anti-inflammatory agent (AB120643)
ab84833 staining Aryl hydrocarbon receptor in MDA-MB-231 cells treated with tranilast (ab120643), by ICC/IF. Increase in Aryl hydrocarbon receptor expression correlates with increased concentration of tranilast, as described in literature.
The cells were incubated at 37°C for 24h in media containing different concentrations of ab120643 (telmisartan) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab84833 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight® 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
- Chemical Structure
Lab
Chemical Structure - Tranilast, Anti-inflammatory agent (AB120643)
2D chemical structure image of ab120643, Tranilast, Anti-inflammatory agent
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Publications (1)
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Oncotarget 8:88670-88688 PubMed29179466
2017
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