MW 300.44 g/mol, Purity >99%. Vitamin A metabolite. Induces apoptosis, shows antimitotic and antitumor activity. Differentiates various stem cells and neural progenitor cells. 3D Growth matrix component used in kidney organoid generation; also a component of brain organoid differentiation media.
302-79-4
> 99%
Solid
300.44 g/mol
C20H28O2
Synthetic
MW 300.44 g/mol, Purity >99%. Vitamin A metabolite. Induces apoptosis, shows antimitotic and antitumor activity. Differentiates various stem cells and neural progenitor cells. 3D Growth matrix component used in kidney organoid generation; also a component of brain organoid differentiation media.
302-79-4
> 99%
Solid
300.44 g/mol
C20H28O2
Synthetic
Soluble in DMSO to 25 mM. Soluble in ethanol to 10 mM.
Vitamin A metabolite. Induces apoptosis, shows antimitotic and antitumor activity. Differentiates various stem cells and neural progenitor cells. 3D Growth matrix component used in kidney organoid generation; also a component of brain organoid differentiation media.
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Ambient - Can Ship with Ice
-20°C
-20°C
It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions, The product can be stored for up to 12 months
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2D chemical structure image of ab120728, trans-Retinoic acid, Stem cell differentiator
Anti-Oct4 antibody ab19857 staining Oct4 in F9 cells treated with trans-retinoic acid (ab120728), by ICC/IF. Decrease of Oct4 expression correlates with increased concentration of trans-retinoic acid, as described in literature.
The cells were incubated at 37°C for 2 days in media containing different concentrations of ab120728 (trans-retinoic acid) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with Anti-Oct4 antibody ab19857 (1 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-rabbit polyclonal antibody (Goat Anti-Rabbit IgG H&L (DyLight® 488) preadsorbed ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
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