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MW 302.37 Da, Purity >99%. Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

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Images

Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (AB146598), expandable thumbnail

Key facts

CAS number
58880-19-6
Purity
> 99%
Form
Liquid
Molecular weight
302.37 Da
Molecular formula
C17H22N2O3
PubChem identifier
444732
Nature
Synthetic

Alternative names

Recommended products

MW 302.37 Da, Purity >99%. Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

Key facts

Purity
> 99%
PubChem identifier
444732
Biochemical name
trichostatin A
Biological description

Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

Canonical SMILES
CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Isomeric SMILES
C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
InChI
InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
InChIKey
RTKIYFITIVXBLE-QEQCGCAPSA-N
IUPAC name
(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes

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1 product image

  • Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (ab146598), expandable thumbnail

    Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (ab146598)

    2D chemical structure image of ab146598, Trichostatin A (DMSO solution), histone deacetylase inhibitor

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Product protocols

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