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MW 302.37 Da, Purity >99%. Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

Also available as a solid (ab120850).

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Images

Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (AB146598), expandable thumbnail

Key facts

CAS number

58880-19-6

Purity

> 99%

Form

Liquid

Molecular weight

302.37 Da

Molecular formula

C17H22N2O3

PubChem identifier

444732

Nature

Synthetic

Alternative names

Recommended products

MW 302.37 Da, Purity >99%. Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

Also available as a solid (ab120850).

Key facts

Purity

> 99%

PubChem identifier

444732

Biochemical name

trichostatin A

Biological description

Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

Also available as a solid (ab120850).

Canonical SMILES

CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C

Isomeric SMILES

C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C

InChI

InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1

InChIKey

RTKIYFITIVXBLE-QEQCGCAPSA-N

IUPAC name

(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (ab146598), expandable thumbnail

    Chemical Structure - Trichostatin A (DMSO solution), histone deacetylase inhibitor (ab146598)

    2D chemical structure image of ab146598, Trichostatin A (DMSO solution), histone deacetylase inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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