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AB120936

Triciribine, inhibitor of Akt activation

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MW 320.31 g/mol, Purity >98%. Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
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Chemical Structure - Triciribine, inhibitor of Akt activation (AB120936)
  • Chemical Structure

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Chemical Structure - Triciribine, inhibitor of Akt activation (AB120936)

2D chemical structure image of ab120936, Triciribine, inhibitor of Akt activation

Key facts

CAS number

35943-35-2

Purity

>98%

Form

Solid

form

Molecular weight

320.31 g/mol

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>6</sub>N<sub>6</sub>O<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 75 mM

Soluble in ethanol to 10 mM

Biological description

Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

Isomeric smiles

OC[C@H]1O[C@H](C(O)C1O)N1CC2C(N)NN(C)C3NCNC1C23

IUPAC Name

1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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