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MW 320.31 g/mol, Purity >98%. Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

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Images

Chemical Structure - Triciribine, inhibitor of Akt activation (AB120936), expandable thumbnail

Key facts

CAS number
35943-35-2
Purity
> 98%
Form
Solid
Molecular weight
320.31 g/mol
Molecular formula
C13H16N6O4
Nature
Synthetic

Target data

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MW 320.31 g/mol, Purity >98%. Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

Key facts

Purity
> 98%
Solubility

Soluble in DMSO to 75 mM.

Soluble in ethanol to 10 mM.

Biological description

Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

Isomeric SMILES
OC[C@H]1O[C@H](C(O)C1O)N1CC2C(N)NN(C)C3NCNC1C23
IUPAC name
1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Triciribine, inhibitor of Akt activation (ab120936), expandable thumbnail

    Chemical Structure - Triciribine, inhibitor of Akt activation (ab120936)

    2D chemical structure image of ab120936, Triciribine, inhibitor of Akt activation

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Product protocols

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