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AB144562

Trovafloxacin mesylate, Fluoroquinolone antibiotic agent

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MW 512.46 g/mol, Purity >98%. Fluoroquinolone antibiotic agent. Topoisomerase IV and DNA gyrase inhibitor. Reversibly inhibits DNA synthesis. Inhibits PANX1 (IC50 = 4 μM). Shows antibiotic effects in vivo (MIC90 = 244 nM, pneumococci).
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Chemical Structure - Trovafloxacin mesylate, Fluoroquinolone antibiotic agent (AB144562)
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Chemical Structure - Trovafloxacin mesylate, Fluoroquinolone antibiotic agent (AB144562)

2D chemical structure image of ab144562, Trovafloxacin mesylate, Fluoroquinolone antibiotic agent

Key facts

CAS number

147059-75-4

Purity

>98%

Form

Solid

form

Molecular weight

512.46 g/mol

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>5</sub>F<sub>3</sub>N<sub>4</sub>O<sub>3</sub>.CH<sub>3</sub>SO<sub>3</sub>H

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Fluoroquinolone antibiotic agent. Topoisomerase IV and DNA gyrase inhibitor. Reversibly inhibits DNA synthesis. Inhibits PANX1 (IC50 = 4 μM). Shows antibiotic effects in vivo (MIC90 = 244 nM, pneumococci).

Isomeric smiles

CS(=O)(=O)O.O=C(O)C2=CN(C1NC(C(F)CC1C2=O)N3C[C@@H]4[C@@H](N)[C@@H]4C3)C5CCC(F)CC5F

InChi

InChI=1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChiKey

DYNZICQDCVYXFW-AHZSKCOESA-N

IUPAC Name

7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate

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Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Secondary Antibodies

AB97180

Goat Anti-Rat IgM mu chain (HRP)

  • 5
  • 1
Secondary Antibodies

AB125919

Rabbit monoclonal [H19-5] Anti-Human kappa light chain

RabMAb|Recombinant

Western blot - Rabbit monoclonal [H19-5] Anti-Human kappa light chain (AB125919)

  • 0
  • 0
Secondary Antibodies

AB172329

Rat monoclonal [SB76b] Anti-Mouse IgG3 gamma chain (Alexa Fluor® 647)

Flow Cytometry - Rat monoclonal [SB76b] Anti-Mouse IgG3 gamma chain (Alexa Fluor® 647) (AB172329)

  • 0
  • 0
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Product promise

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