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AB120927

URB754, Monoacylglycerol lipase inhibitor

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MW 266.3 g/mol, Purity >98%. Reported potent and non-competitive monoacylglycerol lipase (MAGL) inhibitor (IC50 = 200 nM). Inhibits FAAH (IC50 = 32 μM) and binds weakly to the rat CB1 receptor (IC50 = 3.8 μM). Shows vasodilatory activity.
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Chemical Structure - URB754, Monoacylglycerol lipase inhibitor (AB120927)
  • Chemical Structure

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Chemical Structure - URB754, Monoacylglycerol lipase inhibitor (AB120927)

2D chemical structure image of ab120927, URB754, Monoacylglycerol lipase inhibitor

Key facts

CAS number

86672-58-4

Purity

>98%

Form

Solid

form

Molecular weight

266.3 g/mol

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>4</sub>N<sub>2</sub>O<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Biological description

Reported potent and non-competitive monoacylglycerol lipase (MAGL) inhibitor (IC50 = 200 nM). Inhibits FAAH (IC50 = 32 μM) and binds weakly to the rat CB1 receptor (IC50 = 3.8 μM). Shows vasodilatory activity.

Canonical smiles

CC1CCC(CC1)NC1NC2CCC(C)CC2C(=O)O1

IUPAC Name

6-Methyl-2-[(4-methylphenyl)amino]-1-benzoxazin-4-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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