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MW 456.7 Da, Purity >99%. Pentacyclic triterpenoid. Suppresses NF-κB activation in vitro. Antitumourigenic, antiangiogenic, anti-inflammatory and proapoptotic effects.
Alternative names=11-DH, 11-beta hydroxysteroid dehydrogenase, type 1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11DH, ADR, AKR1B 1, ALDR_HUMAN, ALR2, AR, ARO, ARO1, Aldehyde reductase, Aldehyde reductase 1, Aldo-keto reductase family 1 member B1, Aldose reductase, Aromatase, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, BG 37, CORTRD2, CP19A_HUMAN, CPV1, CYAR, CYP19, CYPXIX, Corticosteroid 11-beta-dehydrogenase isozyme 1, Cyp19a1, Cytochrome P-450AROM, Cytochrome P450 19A1, Cytochrome P450, family 19, subfamily A, polypeptide 1, Cytochrome P450, subfamily XIX (aromatization of androgens), DHI1_HUMAN, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DPOLB_HUMAN, Estrogen synthase, Estrogen synthetase, G protein coupled bile acid receptor BG 37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GPBAR 1, GPBAR_HUMAN, GPCR, GPCR 19, GPR 131, HDL, HSD 11, HSD11B, HSD11L, Hydroxysteroid (11 beta) dehydrogenase, Hydroxysteroid (11 beta) dehydrogenase 1, IMD42, Lii5 2 CTCL tumor antigen, Liver-specific organic anion transporter 1, Low Km aldose reductase, M-BAR, MGC104309, MGC125976, MGC129539, MGC131774, MGC13539, MGC1804, MGC40597, Membrane bile acid receptor, Membrane-type receptor for bile acids, Microsomal monooxygenase, NF kappa B p65delta3, NFKB3, NFkB p65, NR1F3, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor kappa-B, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, OATP-2, OATP-C, OTTHUMP00000162543, OTTHUMP00000198350, OTTHUMP00000233473, OTTHUMP00000233474, OTTHUMP00000233475, OTTHUMP00000233476, OTTHUMP00000233900, P 450AROM, Pol B, Pol beta, Polymerase (DNA directed) beta, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, SDR26C1, SLC21A6, SLCO1B1, SO1B1_HUMAN, Sodium-independent organic anion-transporting polypeptide 2, Solute carrier family 21 member 6, Solute carrier organic anion transporter family member 1B1, TF65_HUMAN, TGR 5, TOR, Transcription factor NFKB3, Transcription factor p65, V rel avian reticuloendotheliosis viral oncogene homolog A, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65, aldo-keto reductase family 1, member B1 (aldose reductase), aldr 1, flavoprotein-linked monooxygenase, hBG 37, hGPCR 19, nfkappabp65, p65, p65 NF kappaB, p65 NFkB, relA, short chain dehydrogenase/reductase family 26C, member 1, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)), v rel reticuloendotheliosis viral oncogene homolog A (avian)
77-52-1
> 99%
Solid
456.7 Da
C30H48O3
64945
Synthetic
MW 456.7 Da, Purity >99%. Pentacyclic triterpenoid. Suppresses NF-κB activation in vitro. Antitumourigenic, antiangiogenic, anti-inflammatory and proapoptotic effects.
Alternative names=11-DH, 11-beta hydroxysteroid dehydrogenase, type 1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11DH, ADR, AKR1B 1, ALDR_HUMAN, ALR2, AR, ARO, ARO1, Aldehyde reductase, Aldehyde reductase 1, Aldo-keto reductase family 1 member B1, Aldose reductase, Aromatase, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, BG 37, CORTRD2, CP19A_HUMAN, CPV1, CYAR, CYP19, CYPXIX, Corticosteroid 11-beta-dehydrogenase isozyme 1, Cyp19a1, Cytochrome P-450AROM, Cytochrome P450 19A1, Cytochrome P450, family 19, subfamily A, polypeptide 1, Cytochrome P450, subfamily XIX (aromatization of androgens), DHI1_HUMAN, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DPOLB_HUMAN, Estrogen synthase, Estrogen synthetase, G protein coupled bile acid receptor BG 37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GPBAR 1, GPBAR_HUMAN, GPCR, GPCR 19, GPR 131, HDL, HSD 11, HSD11B, HSD11L, Hydroxysteroid (11 beta) dehydrogenase, Hydroxysteroid (11 beta) dehydrogenase 1, IMD42, Lii5 2 CTCL tumor antigen, Liver-specific organic anion transporter 1, Low Km aldose reductase, M-BAR, MGC104309, MGC125976, MGC129539, MGC131774, MGC13539, MGC1804, MGC40597, Membrane bile acid receptor, Membrane-type receptor for bile acids, Microsomal monooxygenase, NF kappa B p65delta3, NFKB3, NFkB p65, NR1F3, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor kappa-B, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, OATP-2, OATP-C, OTTHUMP00000162543, OTTHUMP00000198350, OTTHUMP00000233473, OTTHUMP00000233474, OTTHUMP00000233475, OTTHUMP00000233476, OTTHUMP00000233900, P 450AROM, Pol B, Pol beta, Polymerase (DNA directed) beta, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, SDR26C1, SLC21A6, SLCO1B1, SO1B1_HUMAN, Sodium-independent organic anion-transporting polypeptide 2, Solute carrier family 21 member 6, Solute carrier organic anion transporter family member 1B1, TF65_HUMAN, TGR 5, TOR, Transcription factor NFKB3, Transcription factor p65, V rel avian reticuloendotheliosis viral oncogene homolog A, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65, aldo-keto reductase family 1, member B1 (aldose reductase), aldr 1, flavoprotein-linked monooxygenase, hBG 37, hGPCR 19, nfkappabp65, p65, p65 NF kappaB, p65 NFkB, relA, short chain dehydrogenase/reductase family 26C, member 1, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)), v rel reticuloendotheliosis viral oncogene homolog A (avian)
77-52-1
> 99%
Solid
456.7 Da
C30H48O3
64945
Synthetic
One part dissolves in 88 parts methanol, 178 alcohol, (35 boiling alcohol), 140 ether, 388 chloroform, 1675 carbon disulfide. Moderately soluble in acetone. Soluble in hot glacial acetic acid and in 2% alcoholic NaOH. Insoluble in petroleum ether. In water, 1.02X10-4 mg/L at 25 °C (est).
Ursolic acid
Pentacyclic triterpenoid. Suppresses NF-κB activation in vitro. Antitumourigenic, antiangiogenic, anti-inflammatory and proapoptotic effects.
CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O
C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O
InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
WCGUUGGRBIKTOS-GPOJBZKASA-N
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Ambient - Can Ship with Ice
-20°C
Store under desiccating conditions, The product can be stored for up to 12 months
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