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MW 538.7 Da, Purity >=98%. A competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC50 = 9.6 μM) in HEK-293 cells.

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Publications

Key facts

Purity
>= 98%
Form
Solid
Molecular weight
538.7 Da
Molecular formula
C34H38N2O4
PubChem identifier
134603246
Nature
Synthetic

Target data

Recommended products

MW 538.7 Da, Purity >=98%. A competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC50 = 9.6 μM) in HEK-293 cells.

Key facts

Purity
>= 98%
PubChem identifier
134603246
Solubility

>50 mg/ml in DMSO.

Biochemical name
2-Amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]butanoic acid
Biological description

A competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC50 = 9.6 μM) in HEK-293 cells.

Canonical SMILES
CC1=CC(=CC=C1)COC2=CC=CC=C2CN(CCC(C(=O)O)N)CC3=CC=CC=C3OCC4=CC=CC(=C4)C
InChI
InChI=1S/C34H38N2O4/c1-25-9-7-11-27(19-25)23-39-32-15-5-3-13-29(32)21-36(18-17-31(35)34(37)38)22-30-14-4-6-16-33(30)40-24-28-12-8-10-26(2)20-28/h3-16,19-20,31H,17-18,21-24,35H2,1-2H3,(H,37,38)
InChIKey
YGKNVAAMULVFNN-UHFFFAOYSA-N
IUPAC name
2-amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]butanoic acid

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark

Notes

This product is manufactured by BioVision, an Abcam company and was previously called B2563 V-9302. B2563-5 is the same size as the 5 mg size of ab287091.

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