MW 637.74 g/mol. Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.
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- Food and chemical toxicology : an international jo 128:256-2662019Decreased levels of H3K9ac and H3K27ac in the promotor region of ovarian P450 aromatase mediated low estradiol synthesis in female offspring rats induced by prenatal nicotine exposure as well as in human granulosa cells after nicotine treatment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuanlan Fan et. al.PubMed 30959089
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 123:314-3252018Excitotoxicity and compensatory upregulation of GAD67 in fetal rat hippocampus caused by prenatal nicotine exposure are associated with inhibition of the BDNF pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYun Pei,Zhexiao Jiao,Wanting Dong,Linguo Pei,Xia He,Hui Wang,Dan XuPubMed 30389584
- Toxicology letters 296:31-382018Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuohui Zhang et. al.PubMed 30036686
- Toxicology and applied pharmacology 344:1-122018nAChRs-ERK1/2-Egr-1 signaling participates in the developmental toxicity of nicotine by epigenetically down-regulating placental 11β-HSD2.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJin Zhou et. al.PubMed 29486207
Key facts
- CAS number
- 50700-72-6
- Form
- Solid
- Molecular weight
- 637.74 g/mol
- Molecular formula
- C34H57BrN2O4
- Nature
- Synthetic
Recommended products
MW 637.74 g/mol. Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.
Key facts
- CAS number
- 50700-72-6
- Form
- Solid
- Molecular weight
- 637.74 g/mol
- Molecular formula
- C34H57BrN2O4
- Nature
- Synthetic
- Solubility
Soluble in DMSO to 100 mM.
Soluble in ethanol to 100 mM.
Soluble in water to 25 mM.
- Biological description
Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.
- Isomeric SMILES
- [BR-].C[N+]1(CCCCC1)C2C[C@H]3C4CC[C@H]5C[C@H](OC(C)=O)C(CC5(C)[C@H]4CCC3(C)C2OC(C)=O)N6CCCCC6
- InChI
- InChI=1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26?,27-,28-,29?,30?,31-,32?,33?,34?;/m0./s1
- InChIKey
- VEPSYABRBFXYIB-HDEGTDFTSA-M
- IUPAC name
- 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- Ambient
- Appropriate long-term storage conditions
- Ambient
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Vecuronium bromide, Competitive nicotinic acetylcholine receptor antagonist (ab120536)
2D chemical structure image of ab120536, Vecuronium bromide, Competitive nicotinic acetylcholine receptor antagonist
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