MW 673.8 Da, Purity >97%. Alkaloid toxin found in *Liliaceae* plants. Causes persistent opening of the voltage-gated Na+ channel and reduces its single-channel conductance. Channel opener.
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- Neuron 110:644-657.e62022A novel reticular node in the brainstem synchronizes neonatal mouse crying with breathing.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXin Paul Wei,Matthew Collie,Bowen Dempsey,Gilles Fortin,Kevin YacklePubMed 34998469
- Pain 161:1100-11082020An unbiased and efficient assessment of excitability of sensory neurons for analgesic drug discovery.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZainab A Mohammed,Katerina Kaloyanova,Mohammed A NassarPubMed 31929383
- PloS one 12:e01828482017Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSilmara R Sousa et. al.PubMed 28880874
- Scientific reports 7:452212017Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZainab A Mohammed et. al.PubMed 28338073
- The Journal of biological chemistry 291:17049-652016Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSónia Troeira Henriques et. al.PubMed 27311819
- Pain 154:1999-20062013Analgesic treatment of ciguatoxin-induced cold allodynia.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKatharina Zimmermann et. al.PubMed 23778293
Key facts
- CAS number
- 71-62-5
- Purity
- > 97%
- Form
- Solid
- Source
- Liliaceae sp.
- Molecular weight
- 673.8 Da
- Molecular formula
- C36H51NO11
- PubChem identifier
- 6610253
- Nature
- Native
Recommended products
MW 673.8 Da, Purity >97%. Alkaloid toxin found in *Liliaceae* plants. Causes persistent opening of the voltage-gated Na+ channel and reduces its single-channel conductance. Channel opener.
Key facts
- CAS number
- 71-62-5
- Purity
- > 97%
- Form
- Solid
- Source
- Liliaceae sp.
- Molecular weight
- 673.8 Da
- Molecular formula
- C36H51NO11
- PubChem identifier
- 6610253
- Nature
- Native
- Solubility
Soluble in ethanol to 100 mM.
- Biochemical name
- Veratridine, >=90% (HPLC), powder
- Biological description
Alkaloid toxin found in *Liliaceae* plants. Causes persistent opening of the voltage-gated Na+ channel and reduces its single-channel conductance. Channel opener.
- Canonical SMILES
- CC1CCC2C(C3(C(CC4(C5CCC6C7(C5(CC4(C3CN2C1)O)OC6(C(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
- Isomeric SMILES
- CC1CCC2[C@@]([C@]3([C@H](C[C@]4(C5CCC6[C@]7([C@]5(C[C@]4(C3CN2C1)O)O[C@@]6(C(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
- InChI
- InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19?,23?,24?,25?,26?,27-,28?,30-,31+,32+,33+,34+,35-,36-/m0/s1
- InChIKey
- FVECELJHCSPHKY-FCSYLLAHSA-N
- IUPAC name
- [(1R,10R,11S,12S,14R,19S,23S,25R)-1,10,11,12,14,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 3,4-dimethoxybenzoate
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Veratridine, Na+ channel opener (ab120279)
2D chemical structure image of ab120279, Veratridine, Na+ channel opener
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