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MW 270.3 Da, Purity >98%. Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.
- Purity
> 98%
- Form
Solid
- Molecular weight
270.3 Da
- Molecular formula
C12H14O5S
- PubChem identifier
607791
- Nature
Synthetic
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MW 270.3 Da, Purity >98%. Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.
Key facts
- Purity
> 98%
- Form
Solid
- Molecular weight
270.3 Da
- Molecular formula
C12H14O5S
- PubChem identifier
607791
- Nature
Synthetic
- Biochemical name
o-Carbethoxy-5-methylthio vanillin
- Biological description
Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.
- Canonical SMILES
CCOC(=O)OC1=C(C=C(C=C1SC)C=O)OC
- InChI
InChI=1S/C12H14O5S/c1-4-16-12(14)17-11-9(15-2)5-8(7-13)6-10(11)18-3/h5-7H,4H2,1-3H3
- InChIKey
FWZSQEQKXCQFCN-UHFFFAOYSA-N
- IUPAC name
ethyl (4-formyl-2-methoxy-6-methylsulfanylphenyl) carbonate
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 1957 Vinorelbine Tartrate. 1957-25 is the same size as the 25 mg size of ab142167.
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