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MW 270.3 Da, Purity >98%. Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.

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Purity

> 98%

Form

Solid

Molecular weight

270.3 Da

Molecular formula

C12H14O5S

PubChem identifier

607791

Nature

Synthetic

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Shipping To:
United States

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MW 270.3 Da, Purity >98%. Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.

Key facts

Purity

> 98%

PubChem identifier

607791

Biochemical name

o-Carbethoxy-5-methylthio vanillin

Biological description

Selective mitotic microtubule antagonist. Inhibits multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Blocks metaphase/anaphase transition (IC50 = 3.8 nM). Active in vivo. Orally active. Shows antimitotic and antitumor activity.

Canonical SMILES

CCOC(=O)OC1=C(C=C(C=C1SC)C=O)OC

InChI

InChI=1S/C12H14O5S/c1-4-16-12(14)17-11-9(15-2)5-8(7-13)6-10(11)18-3/h5-7H,4H2,1-3H3

InChIKey

FWZSQEQKXCQFCN-UHFFFAOYSA-N

IUPAC name

ethyl (4-formyl-2-methoxy-6-methylsulfanylphenyl) carbonate

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Notes

This product is manufactured by BioVision, an Abcam company and was previously called 1957 Vinorelbine Tartrate. 1957-25 is the same size as the 25 mg size of ab142167.

Product promise

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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