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AB144862

Vitexin (Apigenin 8-C-glucoside), Antioxidant agent

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MW 432.4 Da, Purity >98%. Antioxidant agent. Potent glucosidase inhibitor (IC50 = 48 nM). HIF-1 α inhibitor. Inhibits TNF-α, IL-1β, IL-6, and IL-33 production. Shows antinociceptive, anti-inflammatory, and antioxidant effects in vivo..

Key facts

CAS number

3681-93-4

Purity

>98%

Source

Crataegus pinnatifida

Molecular weight

432.4 Da

Molecular formula

C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>0</sub>O<sub>1</sub><sub>0</sub>

PubChem

5280441

Nature

Native

Solubility

Soluble in water

Soluble in DMSO

Biochemical name

Vitexin

Biological description

Antioxidant agent. Potent glucosidase inhibitor (IC50 = 48 nM). HIF-1 α inhibitor. Inhibits TNF-α, IL-1β, IL-6, and IL-33 production. Shows antinociceptive, anti-inflammatory, and antioxidant effects in vivo.

Canonical smiles

C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O

Isomeric smiles

C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O

InChi

InChI=1S/C21H20O10/c22-7-14-17(27)18(28)19(29)21(31-14)16-11(25)5-10(24)15-12(26)6-13(30-20(15)16)8-1-3-9(23)4-2-8/h1-6,14,17-19,21-25,27-29H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChiKey

SGEWCQFRYRRZDC-VPRICQMDSA-N

IUPAC Name

5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

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