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AB141424

VU0255035, muscarinic M1 antagonist

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(1 Publication)

MW 194.62 Da, Purity >98%. Highly selective, competitive muscarinic M1 antagonist (Ki = 14.87 nM). 75-fold selectivity over other receptor subtypes for orthosteric site. Blood-brain barrier permeable.
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Chemical Structure - VU0255035, muscarinic M1 antagonist (AB141424)
  • Chemical Structure

Lab

Chemical Structure - VU0255035, muscarinic M1 antagonist (AB141424)

2D chemical structure image of ab141424, VU0255035, muscarinic M1 antagonist

Key facts

CAS number

1135243-19-4

Purity

>98%

Form

Solid

form

Molecular weight

194.62 Da

Molecular formula

CrFeNiSi+<sub>6</sub>

PubChem

22247365

Nature

Synthetic

Solubility

Soluble in DMSO to 50mM

Biochemical name

CID 22247365

Biological description

Highly selective, competitive muscarinic M1 antagonist (Ki = 14.87 nM). 75-fold selectivity over other receptor subtypes for orthosteric site. Blood-brain barrier permeable.

Canonical smiles

[Si].[Cr+2].[Fe+2].[Ni+2]

Isomeric smiles

[Si].[Cr+2].[Fe+2].[Ni+2]

InChi

InChI=1S/Cr.Fe.Ni.Si/q3*+2;

InChiKey

SSZLDYAPDVBSBK-UHFFFAOYSA-N

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of neuroscience : the official journal of the Society for Neuroscience 43:722-735 PubMed36535767

2022

Differential Regulation of Prelimbic and Thalamic Transmission to the Basolateral Amygdala by Acetylcholine Receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah C Tryon,Joshua X Bratsch-Prince,James W Warren,Grace C Jones,Alexander J McDonald,David D Mott
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