Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor

• Chemical Structure

Lab

Chemical Structure - Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor (AB144494)

2D chemical structure image of ab144494, Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor

• FuncS

PubMed

Functional Studies - Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor (AB144494)

Representative morphology and membrane potential responses to current step injection in hESMNs at 3 different times in vitro.

Imaging of cells fixed after patch-clamp recordings indicate that recorded cells express the Hb9 : : GFP reporter transgene (A-C,E,G,and I). Voltage responses and imaging in the same rows are taken from same neurons. The neurons for A-C are same as that shown in F and G. D,F,H show examples of voltage responses to current steps recorded from 3 neurons current-clamped at −58 mV, −60 mV, and −55 mV, respectively. Bottom traces in D,F, and H show injected currents. Scale bars in images are 50 μm.

Only part of full image panel shown.

Cells were pre-treated with ab144494.

Takazawa et al PLoS One. 2012;7(7):e40154. doi: 10.1371/journal.pone.0040154. Epub 2012 Jul 3. Fig 2. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/