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AB291110

Y-27632, Sterile-Filtered

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Y-27632, Sterile-Filtered (CAS:129830-38-2)(ab291110) is a potent cell-permeable and selective Rho kinase (ROCK) inhibitor. Y-27632, Dihydrochloride has a molecular weight of 320.3 g/mol.

Key facts

CAS number

129830-38-2

Purity

>99%

Form

Liquid

form

Molecular weight

320.3 Da

Molecular formula

C<sub>1</sub><sub>4</sub>H<sub>2</sub><sub>3</sub>Cl<sub>2</sub>N<sub>3</sub>O

PubChem

9901617

Nature

Synthetic

Biochemical name

(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride

Biological description

Selective Rho kinase inhibitor.

Canonical smiles

CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

Isomeric smiles

C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

InChi

InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1

InChiKey

IDDDVXIUIXWAGJ-DDSAHXNVSA-N

IUPAC Name

4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride

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Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB252881

Anti-GFP antibody [3H9]

BOND RX™ Validated|Recombinant|Lab Essentials|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [3H9] (AB252881)

  • 0
  • 0
Primary Antibodies

AB15580

Anti-Ki67 antibody

BOND RX™ Validated|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody (AB15580)

  • 5
  • 230
Primary Antibodies

AB7817

Anti-alpha smooth muscle Actin antibody [1A4]

KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha smooth muscle Actin antibody [1A4] (AB7817)

  • 5
  • 105
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Product details

Y-27632, Sterile-Filtered (Dihydrochloride), ab291110 inhibits Rho kinases (ROCK) including ROCK1 and ROCK2.

Y-27632, Sterile-Filtered ab291110 (previously known as EZSolution Y-27632, Sterile-Filtered,1994) is a 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride in deionized water.
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
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Product protocols

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Product promise

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