Skip to main content

Y-27632, Sterile-Filtered (ab291110) is a potent cell-permeable and selective Rho kinase (ROCK) inhibitor. Y-27632, Dihydrochloride has a molecular weight of 320.3 g/mol.

- Already pre-dissolved to a concentration of 10 mM
- Achieve your results faster with highly validated, pure and trusted compounds

Be the first to review this product! Submit a review

Key facts

CAS number
129830-38-2
Purity
>= 98%
Form
Liquid
Molecular weight
320.3 Da
Molecular formula
C14H23Cl2N3O
PubChem identifier
9901617
Nature
Synthetic

Alternative names

Recommended products

Y-27632, Sterile-Filtered (ab291110) is a potent cell-permeable and selective Rho kinase (ROCK) inhibitor. Y-27632, Dihydrochloride has a molecular weight of 320.3 g/mol.

- Already pre-dissolved to a concentration of 10 mM
- Achieve your results faster with highly validated, pure and trusted compounds

Key facts

Purity
>= 98%
PubChem identifier
9901617
Biochemical name
(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
Biological description

Selective Rho kinase inhibitor.

Canonical SMILES
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
Isomeric SMILES
C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
InChI
InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1
InChIKey
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
IUPAC name
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes

Notes

Y-27632, Sterile-Filtered (Dihydrochloride), ab291110 inhibits Rho kinases (ROCK) including ROCK1 and ROCK2.

Y-27632, Sterile-Filtered ab291110 (previously known as EZSolution Y-27632, Sterile-Filtered,1994) is a 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride in deionized water.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

0 product images

    Downloads

    Product protocols

    For this product, it's our understanding that no specific protocols are required. You can:

    Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

    For licensing inquiries, please contact partnerships@abcam.com