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AB141383

Z-ATAD-FMK, Caspase-12 inhibitor

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(2 Publications)

MW 540.54 g/mol, Purity >95%. Specific caspase-12 inhibitor. Suppresses annular cell apoptosis and caspase-9 activity in vitro. Active in vitro and in vivo.
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Chemical Structure - Z-ATAD-FMK, Caspase-12 inhibitor (AB141383)
  • Chemical Structure

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Chemical Structure - Z-ATAD-FMK, Caspase-12 inhibitor (AB141383)

2D chemical structure image of ab141383, Z-ATAD-FMK, Caspase-12 inhibitor

Key facts

Purity

>95%

Form

Lyophilized

form

Molecular weight

540.54 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 20 mM

Biological description

Specific caspase-12 inhibitor. Suppresses annular cell apoptosis and caspase-9 activity in vitro. Active in vitro and in vivo.

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Anti-TRIB3 antibody [EPR3151Y]

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Immunoprecipitation - Anti-TRIB3 antibody [EPR3151Y] (AB75846)

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Primary Antibodies

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Anti-XIAP antibody [EPR22189-113]

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Western blot - Anti-XIAP antibody [EPR22189-113] (AB229050)

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Primary Antibodies

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Anti-active YAP1 antibody [EPR19812]

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Western blot - Anti-active YAP1 antibody [EPR19812] (AB205270)

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1152 ATAD-FMK, Z-,. 1152-5 is the same size as the 5 mg size of ab141383.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 13:959938 PubMed36091790

2022

Myricetin activates the Caspase-3/GSDME pathway ER stress induction of pyroptosis in lung cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jicheng Han,Cheng Cheng,Jinxin Zhang,Jinbo Fang,Wei Yao,Yilong Zhu,Zhiru Xiu,Ningyi Jin,Huijun Lu,Xiao Li,Yiquan Li

Redox biology 30:101415 PubMed31901590

2020

Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission.

Applications

Unspecified application

Species

Unspecified reactive species

Jin Wang,Pingjun Zhu,Ruibing Li,Jun Ren,Hao Zhou
View all publications
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Product promise

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