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AB141511

Zamifenacin fumarate, M3 receptor antagonist

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MW 531.6 g/mol, Purity >99%. Selective M3 receptor antagonist (pKi values are 8.52 (M3), 7.93 (M2), 7.90 (M1) and 7.78 (M4) respectively). Inhibits gastrointestinal motility in vivo without causing cardiovascular effects.
1 Images
Chemical Structure - Zamifenacin fumarate, M3 receptor antagonist (AB141511)
  • Chemical Structure

Lab

Chemical Structure - Zamifenacin fumarate, M3 receptor antagonist (AB141511)

2D chemical structure image of ab141511, Zamifenacin fumarate, M3 receptor antagonist

Key facts

CAS number

127308-98-9

Purity

>99%

Form

Solid

form

Molecular weight

531.6 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 25 mM

Biological description

Selective M3 receptor antagonist (pKi values are 8.52 (M3), 7.93 (M2), 7.90 (M1) and 7.78 (M4) respectively). Inhibits gastrointestinal motility in vivo without causing cardiovascular effects.

Isomeric smiles

O=C(O)/C=C/C(=O)O.C1CC(CC2OCOC12)CCN5CCC[C@@H](OC(C3CCCCC3)C4CCCCC4)C5

InChi

InChI=1S/C27H29NO3.C4H4O4/c1-3-8-22(9-4-1)27(23-10-5-2-6-11-23)31-24-12-7-16-28(19-24)17-15-21-13-14-25-26(18-21)30-20-29-25;5-3(6)1-2-4(7)8/h1-6,8-11,13-14,18,24,27H,7,12,15-17,19-20H2;1-2H,(H,5,6)(H,7,8)/b;2-1+/t24-;/m1./s1

InChiKey

PMHKTAIGYOVZEZ-ZHWJIHCSSA-N

IUPAC Name

(3R)-1-[2-(1,3-Benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)piperidine fumarate

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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