JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB145349

Zinpyr-1, Fluorogenic Zn2+ reporter

Be the first to review this product! Submit a review

|

(8 Publications)

MW 823.72 g/mol, Purity >95%. Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.
1 Images
Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (AB145349)
  • Chemical Structure

Lab

Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (AB145349)

2D chemical structure image of ab145349, Zinpyr-1, Fluorogenic Zn2+reporter

Key facts

CAS number

288574-78-7

Purity

>95%

Molecular weight

823.72 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.

Canonical smiles

OC8C(CN(CC1CCCCN1)CC2CCCCN2)C9OC5C(CN(CC3CCCCN3)CC4CCCCN4)C(O)C(CL)CC5C7(OC(=O)C6CCCCC67)C9CC8CL

InChi

InChI=1S/C46H36Cl2N6O5/c47-39-21-37-43(34(41(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30)58-44-35(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)42(56)40(48)22-38(44)46(37)36-16-2-1-15-33(36)45(57)59-46/h1-22,55-56H,23-28H2

InChiKey

QZKKSPLNXQJQRQ-UHFFFAOYSA-N

IUPAC Name

4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein

Excitation/Emission

Ex: 515nm, Em: 515nm

style
left-column

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Assay Kits

AB139484

Autophagy Assay Kit

Functional Studies - Autophagy Assay Kit (AB139484)

  • 4
  • 2
Primary Antibodies

AB283575

Anti-MMP9 antibody [RM1020]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated|Trial Size

Flow Cytometry (Intracellular) - Anti-MMP9 antibody [RM1020] (AB283575)

  • 0
  • 0
Assay Kits

AB102507

Zinc Assay Kit (Colorimetric)

Functional Studies - Zinc Assay Kit (Colorimetric) (AB102507)

  • 5
  • 1
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column

Product protocols

style
left-column

Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Life science alliance 8: PubMed39578074

2024

Membrane transporters modulating the toxicity of arsenic, cadmium, and mercury in human cells.

Applications

Unspecified application

Species

Unspecified reactive species

Andrè Ferdigg,Ann-Katrin Hopp,Gernot Wolf,Giulio Superti-Furga

BMC plant biology 23:20 PubMed36627574

2023

The auxin signaling pathway contributes to phosphorus-mediated zinc homeostasis in maize.

Applications

Unspecified application

Species

Unspecified reactive species

Zhonghua Wang,Yafei Wang,Qingguo Du,Pengshuai Yan,Baogang Yu,Wen-Xue Li,Chun-Qin Zou

BMC neuroscience 23:66 PubMed36384553

2022

Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn-dependent matrix metalloproteinase 9 during the early development.

Applications

Unspecified application

Species

Unspecified reactive species

Kan Zhang,Ruijing Ma,Luping Feng,Peiwen Liu,Shuang Cai,Chaoyang Tong,Jijian Zheng

Nature communications 13:6374 PubMed36289215

2022

Myocardial TRPC6-mediated Zn influx induces beneficial positive inotropy through β-adrenoceptors.

Applications

Unspecified application

Species

Unspecified reactive species

Sayaka Oda,Kazuhiro Nishiyama,Yuka Furumoto,Yohei Yamaguchi,Akiyuki Nishimura,Xiaokang Tang,Yuri Kato,Takuro Numaga-Tomita,Toshiyuki Kaneko,Supachoke Mangmool,Takuya Kuroda,Reishin Okubo,Makoto Sanbo,Masumi Hirabayashi,Yoji Sato,Yasuaki Nakagawa,Koichiro Kuwahara,Ryu Nagata,Gentaro Iribe,Yasuo Mori,Motohiro Nishida

Scientific reports 9:10471 PubMed31320712

2019

The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Moskovskich,Ulrich Goldmann,Felix Kartnig,Sabrina Lindinger,Justyna Konecka,Giuseppe Fiume,Enrico Girardi,Giulio Superti-Furga

The New phytologist 224:202-215 PubMed31131881

2019

Cytokinin-dependent regulatory module underlies the maintenance of zinc nutrition in rice.

Applications

Unspecified application

Species

Unspecified reactive species

Shaopei Gao,Yunhua Xiao,Fan Xu,Xiaokai Gao,Shouyun Cao,Fengxia Zhang,Guodong Wang,Dale Sanders,Chengcai Chu

Journal of neuroscience methods 315:14-16 PubMed30599147

2018

Perfusion alters free zinc levels in the rodent brain.

Applications

Unspecified application

Species

Unspecified reactive species

S L P Lippi,K M Craven,C M Hernandez,G M Grant,J M Flinn

Frontiers in aging neuroscience 10:382 PubMed30524268

2018

A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology.

Applications

Unspecified application

Species

Unspecified reactive species

Stephen L P Lippi,Meghann L Smith,Jane M Flinn
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com