MW 823.72 g/mol, Purity >95%. Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.
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Publications
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- BMC plant biology 23:202023The auxin signaling pathway contributes to phosphorus-mediated zinc homeostasis in maize.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhonghua Wang,Yafei Wang,Qingguo Du,Pengshuai Yan,Baogang Yu,Wen-Xue Li,Chun-Qin ZouPubMed 36627574
- BMC neuroscience 23:662022Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn-dependent matrix metalloproteinase 9 during the early development.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKan Zhang,Ruijing Ma,Luping Feng,Peiwen Liu,Shuang Cai,Chaoyang Tong,Jijian ZhengPubMed 36384553
- Nature communications 13:63742022Myocardial TRPC6-mediated Zn influx induces beneficial positive inotropy through β-adrenoceptors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSayaka Oda,Kazuhiro Nishiyama,Yuka Furumoto,Yohei Yamaguchi,Akiyuki Nishimura,Xiaokang Tang,Yuri Kato,Takuro Numaga-Tomita,Toshiyuki Kaneko,Supachoke Mangmool,Takuya Kuroda,Reishin Okubo,Makoto Sanbo,Masumi Hirabayashi,Yoji Sato,Yasuaki Nakagawa,Koichiro Kuwahara,Ryu Nagata,Gentaro Iribe,Yasuo Mori,Motohiro NishidaPubMed 36289215
- Scientific reports 9:104712019The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnna Moskovskich et. al.PubMed 31320712
- The New phytologist 224:202-2152019Cytokinin-dependent regulatory module underlies the maintenance of zinc nutrition in rice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShaopei Gao,Yunhua Xiao,Fan Xu,Xiaokai Gao,Shouyun Cao,Fengxia Zhang,Guodong Wang,Dale Sanders,Chengcai ChuPubMed 31131881
- Journal of neuroscience methods 315:14-162018Perfusion alters free zinc levels in the rodent brain.Applications:Unspecified applicationReactive species:Unspecified reactive speciesS L P Lippi et. al.PubMed 30599147
- Frontiers in aging neuroscience 10:3822018A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology.Applications:Unspecified applicationReactive species:Unspecified reactive speciesStephen L P Lippi et. al.PubMed 30524268
Key facts
- CAS number
- 288574-78-7
- Purity
- > 95%
- Molecular weight
- 823.72 g/mol
- Nature
- Synthetic
- Excitation/Emission
- Ex: 515nm, Em: 515nm
Recommended products
MW 823.72 g/mol, Purity >95%. Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.
Key facts
- CAS number
- 288574-78-7
- Purity
- > 95%
- Molecular weight
- 823.72 g/mol
- Nature
- Synthetic
- Solubility
Soluble in DMSO.
- Biological description
Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.
- Canonical SMILES
- OC8C(CN(CC1CCCCN1)CC2CCCCN2)C9OC5C(CN(CC3CCCCN3)CC4CCCCN4)C(O)C(CL)CC5C7(OC(=O)C6CCCCC67)C9CC8CL
- InChI
- InChI=1S/C46H36Cl2N6O5/c47-39-21-37-43(34(41(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30)58-44-35(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)42(56)40(48)22-38(44)46(37)36-16-2-1-15-33(36)45(57)59-46/h1-22,55-56H,23-28H2
- InChIKey
- QZKKSPLNXQJQRQ-UHFFFAOYSA-N
- IUPAC name
- 4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein
- Excitation/Emission
- Ex: 515nm, Em: 515nm
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
Product promise
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1 product image
Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (ab145349)
2D chemical structure image of ab145349, Zinpyr-1, Fluorogenic Zn2+reporter
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