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AB145641

ZLN005, PGC-1alpha transcriptional activator

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MW 250.34 Da, Purity >95%. PGC-1α transcriptional activator. Activates AMPK. Stimulates PGC-1α expression. Increases fat oxidation. Improves glucose and pyruvate tolerance. Increases insulin sensitivity. Shows antidiabetic effects in vivo. .
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Chemical Structure - ZLN005, PGC-1alpha transcriptional activator (AB145641)
  • Chemical Structure

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Chemical Structure - ZLN005, PGC-1alpha transcriptional activator (AB145641)

2D chemical structure image of ab145641, ZLN005, PGC-1alpha transcriptional activator

Key facts

CAS number

49671-76-3

Purity

>95%

Form

Solid

form

Molecular weight

250.34 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>1</sub><sub>8</sub>N<sub>2</sub>

PubChem

899323

Nature

Synthetic

Solubility

Soluble in ethanol to 10 mM

Soluble in DMSO to 50 mM

Biochemical name

2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole

Biological description

PGC-1α transcriptional activator. Activates AMPK. Stimulates PGC-1α expression. Increases fat oxidation. Improves glucose and pyruvate tolerance. Increases insulin sensitivity. Shows antidiabetic effects in vivo.

Canonical smiles

CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2

InChi

InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)

InChiKey

LQUNNCQSFFKSSK-UHFFFAOYSA-N

IUPAC Name

2-(4-tert-butylphenyl)-1H-benzimidazole

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2550 ZLN005. 2550-50 is the same size as the 50 mg size of ab145641.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Complementary Products

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Western blot - Anti-PGC1 alpha + beta antibody (AB72230)

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Primary Antibodies

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Western blot - Anti-SIRT1 antibody [19A7AB4] (AB110304)

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Primary Antibodies

AB175932

Anti-NRF1 antibody [EPR5554(N)] - ChIP Grade

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Western blot - Anti-NRF1 antibody [EPR5554(N)] - ChIP Grade (AB175932)

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Primary Antibodies

AB209483

Anti-UCP1 antibody [EPR20381]

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Western blot - Anti-UCP1 antibody [EPR20381] (AB209483)

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