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Hep G2 whole cell lysate suitable for WB. View our extensive range of validated lysates from normal and diseased human, mouse and rat tissue.

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Publications

  • Chemical science 12:10825-108352021
    Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    Hoang Anh T Phan,Sam G Giannakoulias,Taylor M Barrett,Chunxiao Liu,E James Petersson
    PubMed 35355937
  • Cell reports. Medicine 2:1002182021
    Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    Michael S Piepenbrink,Jun-Gyu Park,Fatai S Oladunni,Ashlesha Deshpande,Madhubanti Basu,Sanghita Sarkar,Andreas Loos,Jennifer Woo,Phillip Lovalenti,Derek Sloan,Chengjin Ye,Kevin Chiem,Christopher W Bates,Reuben E Burch,Nathaniel B Erdmann,Paul A Goepfert,Vu L Truong,Mark R Walter,Luis Martinez-Sobrido,James J Kobie
    PubMed 33649747

Key facts

Cell type

Hep G2

Species or organism

Human

Tissue

Liver

Form

Liquid

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Hep G2 whole cell lysate suitable for WB. View our extensive range of validated lysates from normal and diseased human, mouse and rat tissue.

Key facts

Cell type

Hep G2

Form

Liquid

Disease

Hepatocellular Carcinoma

Concentration
Loading...

Cell culture

Biosafety level

EU: 1 US: 1

Adherent/suspension

Adherent

Gender

Male

Storage

Shipped at conditions

Dry Ice

Appropriate long-term storage conditions

-80°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Cell line: HepG2 (Human hepatocellular carcinoma).

Hep G2 whole-cell extract was prepared from cell cultures of the human hepatocellular liver carcinoma HepG2 cell line. These cells are epithelial in morphology and can be induced to exhibit polarization under appropriate culture conditions.

HepG2 cells are most commonly used for studies of hepatocyte function and this HepG2 whole cell lysate is specifically recommended for studies related to:

- human liver diseases, cancers and drug therapies

- HBV etiology

- signaling pathways

- apoptosis

Because of their ability to differentiate into polarized epithelium, these cells are routinely utilized to investigate intracellular protein trafficking, particularly in relation to human liver diseases. HepG2 is the most commonly used cell line in studies pertaining to the regulation of hepatic protein synthesis, particularly the synthesis of acute phase proteins after the onset of a systemic inflammatory response.

In addition, these cells are important for studies related to liver metabolism, liver cancers, liver regeneration, liver cytotoxicity, apoptosis and as a model for hepatitis B virus (HBV) viral etiology.

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Full details and terms and conditions can be found here:
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