Human ABHD17A (FAM108A1) knockout HeLa cell lysate
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ABHD17A KO cell lysate available now. KO validated by. Free of charge wild type control included. Knockout achieved by using CRISPR/Cas9, Insertion of the selection cassette in exon2.
View Alternative Names
Abhydrolase domain-containing protein FAM108A1, C19orf27, MGC5244
- Sanger seq
Unknown
Sanger Sequencing - Human ABHD17A (FAM108A1) knockout HeLa cell lysate (AB263076)
Homozygous : Insertion of the selection cassette in exon2
Product details
Knockout cell lysate achieved by CRISPR/Cas9.
REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
Lysate preparation: Our lysates are made using RIPA buffer to which we add a protease inhibitor cocktail and phosphatase inhibitor cocktail (ratio: 300:100:10). This means that the protein of interest is denatured. If you require a native form of the protein please use the live cell version. Please refer to our lysis protocol for further details on how our lysates are prepared.
User storage instructions: Lyophilizate may be stored at 4°C. After reconstitution, store at -20°C for short-term storage or -80°C for long-term storage.
This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.
What's included?
Properties and storage information
Gene name
Gene editing type
Gene editing method
Knockout validation
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The protein FAM108A1 is potentially involved in cellular signaling and regulation without forming part of any complex well-defined so far in the literature. Researchers speculate this protein may play a part in the regulation of intracellular pathways that control cell growth and differentiation. Despite limited direct data its expression patterns suggest a biological significance in tissue-specific functions especially in neural connections.
Pathways
Researchers found the involvement of proteins similar to FAM108A1 in fundamental pathways like cell proliferation or intracellular communication. Though specific pathway involvement of FAM108A1 itself is still under investigation proteins like ERK1/2 often surface in studies as potentially interacting partners due to their roles in similar biological processes. Understanding its interaction with known pathways can bring clarity to FAM108A1's function.
Quality control
STR analysis
CSF1PO, D13S317, D7S820, D5S818, TH01, D16S539, TPOX
Cell culture
Biosafety level
EU: 2 US: 2
Adherent/suspension
Adherent
Gender
Female
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Product promise
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