Human STK16 knockout HEK-293T cell lysate
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STK16 KO cell lysate available now. KO validated by. Free of charge wild type control included. Knockout achieved by using CRISPR/Cas9, 1 bp deletion in exon3.
View Alternative Names
EDPK, F52, FLJ39635, KRCT, MGC16211, MPSK, MPSK1, Myristoylated and palmitoylated serine/threonine-protein kinase, PKL12, Protein kinase Krct, Protein kinase PKL12, Protein kinase expressed in day 12 fetal liver, STK16_HUMAN, Serine/threonine kinase 16, Serine/threonine-protein kinase 16, TGF-beta-stimulated factor 1, TGFB stimulated factor 1, TSF-1, Transforming growth factor beta stimulated factor 1, Tyrosine protein kinase STK16, hPSK
- Sanger seq
Unknown
Sanger Sequencing - Human STK16 knockout HEK-293T cell lysate (AB259159)
Homozygous : 1 bp deletion in exon3
Product details
Knockout cell lysate achieved by CRISPR/Cas9.
REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
Lysate preparation: Our lysates are made using RIPA buffer to which we add a protease inhibitor cocktail and phosphatase inhibitor cocktail (ratio: 300:100:10). This means that the protein of interest is denatured. If you require a native form of the protein please use the live cell version. Please refer to our lysis protocol for further details on how our lysates are prepared.
User storage instructions: Lyophilizate may be stored at 4°C. After reconstitution, store at -20°C for short-term storage or -80°C for long-term storage.
This product is subject to limited use licenses from The Broad Institute and ERS Genomics Limited, and is developed with patented technology. For full details of the limited use licenses and relevant patents please refer to our limited use license and patent pages.
What's included?
Properties and storage information
Gene name
Gene editing type
Gene editing method
Knockout validation
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
STK16 influences various processes at the cellular level. It participates in vesicular trafficking and Golgi function ensuring proper sorting and delivery of proteins within cells. Although not typically seen as part of large complexes it interacts with several other proteins to exert its biological roles. The protein’s activity affects cell cycle progression and can influence cellular growth and motility.
Pathways
STK16 integrates into key regulatory networks such as the Golgi-associated vesicle budding pathway and cell signaling pathways. These pathways are important for maintaining cellular organization and communication. STK16’s interactions with proteins like COPII in vesicle trafficking and possibly components of the MAPK signaling cascade highlight its connectivity within cellular pathways and its regulatory potential.
Quality control
STR analysis
CSF1PO, D13S317, D7S820, D5S818, TH01, D16S539, TPOX
Cell culture
Biosafety level
EU: 2 US: 2
Adherent/suspension
Adherent
Gender
Female
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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