AB313534
Human CLEC-2 ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human CLEC-2 in Human in Cell Culture Media, Biofluids samples.
View Alternative Names
CLEC2, UNQ721/PRO1384, CLEC1B, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2
1 Images
- sELISA
Supplier Data
Sandwich ELISA - Human CLEC-2 ELISA Kit (AB313534)
Example of standard curve using ab313534. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.
Reactivity data
{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
Product details
Human CLEC-2 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CLEC-2 in serum (human CLEC-2 concentration is pretty low in normal serum/plasma, it may not be detected in this assay), plasma and cell culture supernatants. This assay employs an antibody specific for human CLEC-2 coated on a 96-well plate.
Recovery
[ { "sample": "Serum", "range": "67 - 81 %", "average": "= 72.06" }, { "sample": "Plasma", "range": "69 - 79 %", "average": "= 72.94" }, { "sample": "Cell culture media", "range": "68 - 128 %", "average": "= 91.79" } ]
What's included?
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Properties and storage information
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
- Download websiteProtocolBooklet|en
Target data
C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN (PubMed : 18215137). After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 (PubMed : 18955485).. (Microbial infection) Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (SYK) and initiation of downstream tyrosine phosphorylation events and activation of PLCG2 (PubMed : 16174766, PubMed : 18955485).. (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets (PubMed : 16940507).
Complementary Products
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Product promise
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