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AB313605

Human FGF16 ELISA Kit

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Human FGF16 ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human FGF16 in Human in Cell Culture Media, Biofluids samples.

View Alternative Names

Fibroblast growth factor 16, FGF-16, FGF16

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Sandwich ELISA - Human FGF16 ELISA Kit (AB313605)
  • sELISA

Supplier Data

Sandwich ELISA - Human FGF16 ELISA Kit (AB313605)

Example of standard curve using ab313605. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.

Key facts

Detection method

Colorimetric

Sample types

Cell culture supernatant, Plasma, Serum

Reacts with

Human

Assay type

Sandwich (quantitative)

Sensitivity

= 0.82 ng/mL

Range

0.82 - 200 ng/mL

Assay Platform

Pre-coated microplate (12 x 8 well strips)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Human FGF16 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human FGF16 in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human FGF16 coated on a 96-well plate.
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Recovery

[ { "sample": "Serum", "range": "85 - 96 %", "average": "= 89.05" }, { "sample": "Plasma", "range": "68 - 119 %", "average": "= 92.03" }, { "sample": "Cell culture media", "range": "111 - 131 %", "average": "= 119.5" } ]
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What's included?

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab313605-1x96Tests", "assetComponentDetails": [ { "size":"1 x 1 Unit", "name":"Human FGF-16 Antibody-coated ELISA Plate", "number":"AB313605-CMP09", "productcode":"" }, { "size":"1 x 25 mL", "name":"20X Wash Buffer", "number":"AB313605-CMP04", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Biotinylated Human FGF-16 Detection Antibody", "number":"AB313605-CMP10", "productcode":"" }, { "size":"1 x 12 mL", "name":"TMB One-Step Substrate Reagent", "number":"AB313605-CMP08", "productcode":"" }, { "size":"1 x 8 mL", "name":"Stop Solution; 0.2M Sulfuric Acid", "number":"AB313605-CMP07", "productcode":"" }, { "size":"1 x 15 mL", "name":"5X Assay Diluent B (Item E)", "number":"AB313605-CMP05", "productcode":"" }, { "size":"1 x 200 µL", "name":"500X HRP-Streptavidin", "number":"AB313605-CMP03", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Lyophilized Human FGF-16 Protein Standard", "number":"AB313605-CMP11", "productcode":"" }, { "size":"1 x 30 mL", "name":"Assay Diluent C (Item L)", "number":"AB313605-CMP06", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Fibroblast Growth Factor 16 (FGF16) also known as FGF-16 is a protein belonging to the fibroblast growth factor family. It weighs approximately 27 kDa. FGF16 participates in cellular activities like proliferation and differentiation by binding to fibroblast growth factor receptors. Its expression appears primarily in the heart and skeletal muscles though it may also occur in other tissues under specific conditions.
Biological function summary

FGF16 plays a significant role in tissue repair and development. It does not function alone; rather it acts as part of a signaling complex involving fibroblast growth factor receptors. This interaction is important for cardiac muscle development suggesting its importance in maintaining heart health. Furthermore FGF16 supports the healing processes in damaged muscle tissue contributing to tissue homeostasis.

Pathways

FGF16 is active in both the PI3K-Akt signaling pathway and the MAPK signaling pathway. These pathways manage processes associated with cell survival growth and division. In these pathways FGF16 interacts with proteins like Akt (protein kinase B) and ERK (extracellular signal-regulated kinase) indicating its involvement in the regulation of cell cycle and cellular responses to external stimuli.

FGF16 is linked to cardiac hypertrophy and skeletal muscle-related conditions. Altered FGF16 expression can exacerbate heart muscle enlargement often leading to heart failure. ABI1 another protein associates with FGF16 in cellular signaling affected by these conditions. Moreover any disruption in FGF16's role in skeletal muscle repair may contribute to muscular dystrophies suggesting a potential target for therapeutic intervention.
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Product protocols

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Target data

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
See full target information Fibroblast growth factor 16
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websiteProtocolBooklet
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Product promise

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