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AB47349

Human ICAM1 ELISA Set (without plates)

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(3 Publications)

Human ICAM1 ELISA Set (without plates) is a Sandwich ELISA for the measurement of Human ICAM1 ELISA Set (without plates) in Human in Biofluids, Cell Culture Media samples.

View Alternative Names

CD54, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, ICAM1

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Sandwich ELISA - Human ICAM1 ELISA Set (without plates) (AB47349)
  • sELISA

Supplier Data

Sandwich ELISA - Human ICAM1 ELISA Set (without plates) (AB47349)

Key facts

Sample types

Plasma, Cell culture supernatant, Serum

Reacts with

Human

Assay type

Sandwich

Results type

Quantitative

Sensitivity

< 0.1 ng/mL

Range

0.25 - 8 ng/mL

Assay time

1h 45m

Assay Platform

Reagents

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Abcam's ICAM1 Human in vitro ELISA Set is designed for the quantitative measurement of ICAM1 in cell culture supernatants, buffered solutions, serum, plasma and other body fluids.

This ELISA set is intended to measure human ICAM1 in cell -culture supernatants, as well as in serum and plasma samples. The enclosed procedures provide general guidelines for ELISA preparation. This procedure may need some optimization depending on the plastic, matrix, standard range.

The ICAM1 ELISA Set includes both the capture and the detection antibodies as well as Horse-Radish peroxidase conjugated Streptavidin (HRP-Strep) and TMB which are the reagents used in the colour development step.

Recognizes both natural and recombinant human ICAM1.

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What's included?

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
+4°C
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Product protocols

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Target data

Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL : ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength (PubMed : 3086451, PubMed : 3340213, PubMed : 38195629). Also functions as a ligand receptor of the signaling receptor ITGAM : ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed : 1980124). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (PubMed : 17875742). Promotes cell aggregation in epithelial cells through interaction with MUC1 (PubMed : 11173916).. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins.. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins.. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
See full target information ICAM1
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Tropical medicine & international health : TM & IH 27:727-734 PubMed35761507

2022

Endothelial biomarkers as predictors for haemodialysis need in severe leptospirosis patients (Weil's disease).

Applications

Unspecified application

Species

Unspecified reactive species

Gdayllon Cavalcante Meneses,Pedro Eduardo Andrade de Carvalho Gomes,Gabriela Studart Galdino,Gabriela Freire Bezerra,Ranieri Sales de Souza Santos,Alice Maria Costa Martins,Geraldo Bezerra da Silva Junior,Alexandre Braga Libório,Roberto da Justa Pires Neto,Elizabeth De Francesco Daher

Revista do Instituto de Medicina Tropical de Sao Paulo 63:e44 PubMed34161550

2021

Endothelial activation is associated with albuminuria in multibacillary leprosy.

Applications

Unspecified application

Species

Unspecified reactive species

Louise Donadello Tessarolo,Gdayllon Cavalcante Meneses,Gabriela Freire Bezerra,Thaiany Pereira da Rocha,Isabella Evelyn Prado de Azevedo,Geraldo Bezerra Silva Junior,Maria Araci Andrade Pontes,Elizabeth De Francesco Daher,Alice Maria Costa Martins

Brazilian journal of medical and biological resear 52:e8658 PubMed31778438

2019

Interleukin-6 and adhesion molecules VCAM-1 and ICAM-1 as biomarkers of post-acute myocardial infarction heart failure.

Applications

Unspecified application

Species

Unspecified reactive species

D O C Lino,I A Freitas,G C Meneses,A M C Martins,E F Daher,J H C Rocha,G B Silva Junior
View all publications
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Product promise

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